| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA985127 | B | Activity of Escherichia coli KPC2 assessed as drug hydrolysis by spectrophotometry | Escherichia coli | 5 | single protein format | Scientific Literature | ||
| 2. | ALA985128 | B | Activity of Escherichia coli KPC2 assessed as drug hydrolysis by spectrophotometry relative to cephaloridine | Escherichia coli | 4 | single protein format | Scientific Literature | ||
| 3. | ALA985129 | B | Ratio of Kcat to Km of Escherichia coli KPC2 assessed as drug hydrolysis by spectrophotometry | Escherichia coli | 5 | single protein format | Scientific Literature | ||
| 4. | ALA985130 | B | Ratio of Kcat to Km of Escherichia coli KPC2 assessed as drug hydrolysis by spectrophotometry relative to cephaloridine | Escherichia coli | 4 | single protein format | Scientific Literature | ||
| 5. | ALA3578634 | B | Inhibition of Escherichia coli EC1007 KPC-3 assessed as biapenem MIC at 4 ug/ml by broth microdilution method | Escherichia coli | 1 | single protein format | Scientific Literature | ||
| 6. | ALA3578743 | B | Inhibition of Escherichia coli EC1007 KPC-3 assessed as meropenem MIC at 4 ug/ml by broth microdilution method | Escherichia coli | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3579483 | B | Inhibition of Escherichia coli EC1007 KPC-3 assessed as ertapenem MIC at 4 ug/ml by broth microdilution method | Escherichia coli | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3579668 | B | Inhibition of Escherichia coli EC1007 KPC-3 assessed as imipenem MIC at 4 ug/ml by broth microdilution method | Escherichia coli | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4347935 | B | Inhibition of beta lactamase KPC-2 in Escherichia coli 76 assessed as potentiation of ceftazidime-induced antibacterial activity by measuring ceftazidime MIC at 16 mg/L incubated for 18 hrs by broth dilution method (Rvb = >64 mg/L) | Escherichia coli | 6 | single protein format | Scientific Literature | ||
| 10. | ALA4347944 | B | Inhibition of beta lactamase KPC-2 in Escherichia coli 76 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 16 mg/L incubated for 18 hrs by broth dilution method (Rvb = >64 mg/L) | Escherichia coli | 6 | single protein format | Scientific Literature | ||
| 11. | ALA4374963 | B | Inhibition of beta lactamase KPC-2 in Escherichia coli BAA-2340 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 16 to 20 hrs by broth microdilution assay (Rvb = 4 ug/ml) | Escherichia coli | 7 | single protein format | Scientific Literature | ||
| 12. | ALA4374964 | B | Inhibition of beta lactamase KPC-2 in Escherichia coli 11119 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 50 uM after 16 to 20 hrs by broth microdilution assay (Rvb = 16 ug/ml) | Escherichia coli | 7 | single protein format | Scientific Literature | ||
| 13. | ALA4617678 | B | Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured every 10 secs for 10 mins by spectrophotometric analysis | Escherichia coli | 5 | single protein format | Scientific Literature | ||
| 14. | ALA4818609 | B | Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysis | Escherichia coli | 37 | assay format | Scientific Literature | ||
| 15. | ALA4818625 | B | Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) at 10 uM incubated for 3 mins by spectrophotometric analysis relative to control | Escherichia coli | 31 | assay format | Scientific Literature |
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