| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1820839 | B | Ratio IC50 for lactose to compound for galectin-8 binding to biotinylated neoglycoprotein with p-isothiocyanatophynyl lactoside assessed as lectin-neoglycoprotein complex formation after 1 hr by spectrophotometric analysis | 3 | single protein format | Scientific Literature | |||
| 2. | ALA1820845 | B | Inhibition of galectin-8 binding to biotinylated lectin at cell surface of human SW480 cells at 2 mM by fluorometric analysis | 4 | cell-based format | Scientific Literature | |||
| 3. | ALA1670076 | B | Binding affinity to human galectin-8 by surface plasmon resonance method | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 4. | ALA1670079 | B | Binding affinity to human galectin-8 component 1 by surface plasmon resonance method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 5. | ALA1670080 | B | Binding affinity to human galectin-8 component 2 by surface plasmon resonance method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA1013542 | B | Binding affinity to galectin 8N terminal domain at 20 degC by fluorescence polarization assay | 13 | single protein format | Scientific Literature | |||
| 7. | ALA1252153 | B | Binding affinity to human galectin 8 N-terminal domain at 20 degC by competitive fluorescence polarization assay | Homo sapiens | 35 | single protein format | Scientific Literature | ||
| 8. | ALA3361814 | B | Antagonist activity against human galectin 8 N-terminal domain by fluorescence polarization assay | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 9. | ALA4035422 | B | Inhibition of biotinylated tandem repeat type galectin-8 in human Capan-1 cells after 30 mins by FACS analysis relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 10. | ALA4338793 | B | Binding affinity at recombinant human N-terminal Galectin 8 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assay | Homo sapiens | 24 | assay format | Scientific Literature | ||
| 11. | ALA4338794 | B | Binding affinity at recombinant human C-terminal Galectin 8 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assay | Homo sapiens | 24 | assay format | Scientific Literature | ||
| 12. | ALA4338798 | B | Binding affinity at recombinant human C-terminal Galectin 8 expressed in Escherichia coli BL21 at 2 mM incubated for 5 mins by fluorescence anisotropy assay | Homo sapiens | 18 | assay format | Scientific Literature | ||
| 13. | ALA4338805 | B | Binding affinity at recombinant human N-terminal Galectin 8 expressed in Escherichia coli BL21 at 2 mM incubated for 5 mins by fluorescence anisotropy assay | Homo sapiens | 19 | assay format | Scientific Literature | ||
| 14. | ALA4374290 | B | Displacement of (3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-di-methoxybenzamido)-1,1'-sulfanediyl-di-beta-D-galactopyranoside) fluorescent probe from human His6-tagged galectin-8 N-terminal domain transfected in Escherichia coli BL21 Star (DE3) by competitive fluorescence polarization assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4374291 | B | Displacement of (3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-di-methoxybenzamido)-1,1'-sulfanediyl-di-beta-D-galactopyranoside) fluorescent probe from human His6-tagged galectin-8 C-terminal domain transfected in Escherichia coli BL21 Star (DE3) by competitive fluorescence polarization assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA4429016 | B | Competitive binding affinity to recombinant human galectin-8 N-terminal after 5 mins in presence of fluorescent probe 2-(fluorescein-5-yl-carbonylamino)ethyl beta-D-galactopyranosyl(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosyl(1-3)-beta-D-galactopyranosyl(1-4)-beta-D-glucopyranoside by fluorescence polarization assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 17. | ALA4429028 | B | Competitive binding affinity to human galectin-8 N-terminal after 5 mins in presence of fluorescent probe by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4669861 | B | Antagonist activity at galectin-8 in human SUM159PT cells assessed as reduction in galectin-8-induced IL-8 mRNA expression at 1 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4669862 | B | Antagonist activity at galectin-8 in human SUM159PT cells assessed as reduction in galectin-8-induced IL-6 mRNA expression at 1 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4669863 | B | Antagonist activity at galectin-8 in human SUM159PT cells assessed as reduction in galectin-8-induced IL-6 mRNA expression at 500 uM incubated for 24 hrs by real-time PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature |
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