| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2034450 | B | Inhibition of human DAO measuring H2O2 production by Resorufin/Amplex Red assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 2. | ALA938999 | B | Inhibition of human recombinant DAAO expressed in sf9 insect cells assessed as degradation of D-serine by fluorescence assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 3. | ALA939021 | B | Binding affinity to biotinylated human recombinant DAAO by Biacore assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 4. | ALA958953 | B | Inhibition of human DAO | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 5. | ALA1832105 | B | Inhibition of human recombinant DAAO expressed in Escherichia coli assessed as H2O2 production from D-serine degradation after 30 mins by fluorescence assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 6. | ALA1832106 | B | Inhibition of human DAAO | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA1832107 | B | Binding affinity to human recombinant DAAO by isothermal titration calorimeter analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 8. | ALA1832108 | B | Binding affinity to human recombinant DAAO by kinetic study scintillation proximity assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 9. | ALA1832109 | B | Binding affinity to human recombinant DAAO by steady state study scintillation proximity assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 10. | ALA1832112 | B | Binding affinity to human recombinant DAAO assessed as drug-enzyme complex half life | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 11. | ALA2154050 | B | Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 12. | ALA2327779 | B | Inhibition of human recombinant DAO expressed in Escherichia coli BL21(DE3) by oxygraphic assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA2327780 | B | Inhibition of human recombinant DAO expressed in G418-resistant HEK293/NEO cells assessed as effect on D-alanine level at 83 uM incubated for 30 mins prior to D-alanine addition measured after 24 hrs by HPLC analysis relative to vehicle-treated control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA2327783 | B | Inhibition of N-terminal HA-tagged human recombinant DAO overexpressed in HEK293 cells assessed as increase in D-alanine levels at 17 uM incubated for 30 mins prior to D-alanine addition measured after 24 hrs by HPLC analysis relative to vehicle-treated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2327784 | B | Inhibition of human recombinant DAO expressed in G418-resistant HEK293/NEO cells assessed as effect on D-alanine level at 17 uM incubated for 30 mins prior to D-alanine addition measured after 24 hrs by HPLC analysis relative to vehicle-treated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA2327787 | B | Inhibition of N-terminal HA-tagged human recombinant DAO overexpressed in G418-resistant HEK293 cells assessed as increase in D-alanine levels at 83 uM incubated for 30 mins prior to D-alanine addition measured after 24 hrs by HPLC analysis relative to vehicle-treated control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA2327788 | B | Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 18. | ALA2327789 | B | Inhibition of human recombinant N-terminal His-tagged DAO Y224A mutant expressed in Escherichia coli BL21(DE3) using D-alanine as substrate after 10 mins by Lineweaver-Burk plot analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 19. | ALA2327790 | B | Inhibition of human recombinant N-terminal His-tagged DAO Y224F mutant expressed in Escherichia coli BL21(DE3) using D-alanine as substrate after 10 mins by Lineweaver-Burk plot analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 20. | ALA2327791 | B | Competitive inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-alanine as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 5 | assay format | Scientific Literature |
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