| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1029934 | B | Inhibition of Huntingtin protein aggregation by cell based assay | 29 | ALA1153324 | cell-based format | Scientific Literature | ||
| 2. | ALA1029935 | B | Inhibition of Huntingtin protein aggregation by yeast based assay | 3 | ALA1153324 | single protein format | Scientific Literature | ||
| 3. | ALA1218363 | B | Inhibition of huntingtin-mediated toxicity in yeast transfected with human huntingtin by spotting assay | Homo sapiens | 2 | ALA1212724 | assay format | Scientific Literature | |
| 4. | ALA1243428 | B | Inhibition of EGFP-tagged huntingtin aggregation expressed in african green monkey COS7 cells at 47 uM after 48 hrs by Western blot analysis | 2 | ALA1240327 | cell-based format | Scientific Literature | ||
| 5. | ALA1243429 | B | Inhibition of EGFP-tagged huntingtin aggregation expressed in african green monkey COS7 cells at 43 uM after 48 hrs by Western blot analysis | 1 | ALA1240327 | cell-based format | Scientific Literature | ||
| 6. | ALA1243430 | B | Inhibition of EGFP-tagged huntingtin expressed in african green monkey COS7 cells assessed as protection against protein-induced cell death at 47 uM after 48 hrs by Western blot analysis | 2 | ALA1240327 | cell-based format | Scientific Literature | ||
| 7. | ALA1243431 | B | Inhibition of EGFP-tagged huntingtin expressed in african green monkey COS7 cells assessed as protection against protein-induced cell death at 43 uM after 48 hrs Western blot analysis | 1 | ALA1240327 | cell-based format | Scientific Literature | ||
| 8. | ALA1243461 | B | Inhibition of EGFP-tagged huntingtin aggregation expressed in african green monkey COS7 cells at 140 uM after 24 hrs by Western blot analysis in presence of 0.2 uM rapamycin | 1 | ALA1240327 | cell-based format | Scientific Literature | ||
| 9. | ALA1243462 | B | Inhibition of EGFP-tagged huntingtin aggregation expressed in african green monkey COS7 cells at 43 uM after 24 hrs by Western blot analysis in presence of 0.2 uM rapamycin | 1 | ALA1240327 | cell-based format | Scientific Literature | ||
| 10. | ALA1243463 | B | Inhibition of EGFP-tagged huntingtin aggregation expressed in african green monkey COS7 cells at 47 uM after 24 hrs by Western blot analysis in presence of 0.2 uM rapamycin | 1 | ALA1240327 | cell-based format | Scientific Literature | ||
| 11. | ALA1613918 | F | PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] | Homo sapiens | 18,608 | ALA1201862 | assay format | PubChem BioAssays | |
| 12. | ALA1614003 | F | PUBCHEM_BIOASSAY: qHTS Assay Multiplex Screening to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection in HTT Q25 expressing cells (ATP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471, 1688 ] | Homo sapiens | 32 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 13. | ALA1614147 | F | PUBCHEM_BIOASSAY: qHTS Assay Multiplex Screening to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (Protease release). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471, 1688 ] | Homo sapiens | 136 | ALA1201862 | assay format | PubChem BioAssays | |
| 14. | ALA1614156 | F | PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection confirmation (ATP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471, 1688 ] | Homo sapiens | 72 | ALA1201862 | assay format | PubChem BioAssays | |
| 15. | ALA1738410 | F | PUBCHEM_BIOASSAY: Quantitative High-Throughput Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Summary. (Class of assay: summary) [Related pubchem assays (depositor defined):AID1471, AID1688, AID2669, AID2672, AID2673, AID2713] | Homo sapiens | 11 | ALA1201862 | assay format | PubChem BioAssays | |
| 16. | ALA2346194 | B | Inhibition of HD exon 1 fusion protein with 51 glutamine residues (unknown origin) aggregation expressed in Escherichia coli SURE after 16 hrs by Western blotting analysis | Homo sapiens | 1 | ALA2331315 | assay format | Scientific Literature | |
| 17. | ALA3226740 | B | Inhibition of N-terminal GFP-tagged Htt-exon1-Q25 (unknown origin) transfected in HEK293A cells assessed as reduction of Htt-Q103 aggregate formation at 50 uM after 3 days by fluorescence microscopic analysis | Homo sapiens | 2 | ALA3217572 | cell-based format | Scientific Literature | |
| 18. | ALA3224867 | B | Inhibition of N-terminal Htt-exon1-Q103 (unknown origin) transfected in mouse Neuro2a cells assessed as decrease in soluble and insoluble aggregate formation by Western blotting analysis | Homo sapiens | 1 | ALA3217572 | cell-based format | Scientific Literature | |
| 19. | ALA3224868 | B | Inhibition of N-terminal GFP-tagged Htt-exon1-Q103 (unknown origin) transfected in Neuro2a cells assessed as reduction of Htt-Q103 aggregate formation at 100 uM by fluorescence microscopic analysis | Homo sapiens | 2 | ALA3217572 | cell-based format | Scientific Literature | |
| 20. | ALA3224869 | B | Inhibition of N-terminal GFP-tagged Htt-exon1-Q103 (unknown origin) transfected in HEK293A cells assessed as reduction of Htt-Q103 aggregate formation at 200 uM by filter trap assay | Homo sapiens | 1 | ALA3217572 | cell-based format | Scientific Literature |
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