| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA962979 | B | Inhibition of recombinant ABHD12 transfected in HEK293T cells by SDS-PAGE using rhodamine-tagged FP probe | 2 | cell-based format | Scientific Literature | |||
| 2. | ALA3089724 | B | Inhibition of human ABHD12 overexpressed in HEK293 cells assessed as 2-AG hydrolysis at 1 uM by fluorescent glycerol assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 3. | ALA3405401 | B | Inhibition of human ABHD12 containing pCMV6-XL4-hABHD12 transfected into HEK293 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3405402 | B | Inhibition of human ABHD12 containing pCMV6-XL4-hABHD12 transfected into HEK293 cells at 10 uM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3614955 | B | Inhibition of human ABHD12 expressed in HEK293 cells assessed as remaining enzyme activity at 1 uM pre-incubated for 10 mins before 2-AG substrate addition by HPLC method | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 6. | ALA3614956 | B | Inhibition of human ABHD12 expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3749324 | B | Inhibition of human ABHD12 expressed in HEK239 cells using 2-AG as substrate assessed as glycerol liberation at 10 uM preincubated for 30 mins followed by 2-AG addition measured for 90 mins by fluorescent glycerol assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 8. | ALA3749736 | B | Inhibition of human ABHD12 expressed in HEK239 cells using 2-AG as substrate assessed as glycerol liberation at 1 uM preincubated for 30 mins followed by 2-AG addition measured for 90 mins by fluorescent glycerol assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 9. | ALA4037471 | B | Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after 5 mins by liquid scintillation spectroscopy analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4037475 | B | Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate at 10 uM preincubated for 30 mins followed by substrate addition measured after 5 mins by liquid scintillation spectroscopy analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4155190 | B | Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition and measured after 5 mins by liquid scintillation spectroscopic method | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 12. | ALA4275253 | B | Inhibition of recombinant human ABHD12 expressed in HEK293 cells using 2-OG as substrate pretreated for 30 mins followed by substrate addition and measured after 5 mins by liquid scintillation spectroscopy analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4330039 | A | Inhibition of human ABHD12 expressed in HEK293 cells assessed as residual activity at 10 uM preincubated for 30 mins followed by 1-AG substrate addition and measured after 90 to 120 mins by fluorometric assay relative to control | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 14. | ALA4401197 | B | Inhibition of ABHD12 (unknown origin) expressed in HEK293T cell membranes at 10 uM using 17:1 lyso-PS as substrate preincubated for 20 mins followed by substrate addition measured after 30 mins by LC-MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4401198 | B | Time dependent inhibition of FP-Rh binding to ABHD12 (unknown origin) expressed in HEK293T cell membranes by gel-based ABPP assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4401199 | B | Inhibition of ABHD12 in PMA-differentiated human THP1 cells assessed as increase in TNF-alpha production treated simultaneously with IFN-gamma/LPS for 24 hrs and measured 6 to 24 hrs after stimulation | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4401200 | B | Inhibition of ABHD12 in PMA-differentiated human THP1 cells assessed as increase in IL-1beta production treated simultaneously with IFN-gamma/LPS for 24 hrs and measured 6 to 24 hrs after stimulation | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA4401201 | B | Inhibition of ABHD12 in PMA-differentiated human THP1 cells assessed as increase in CCL3 production treated simultaneously with IFN-gamma/LPS for 24 hrs and measured 6 to 24 hrs after stimulation | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4401202 | B | Inhibition of ABHD12 in PMA-differentiated human THP1 cells assessed as increase in CCL4 production treated simultaneously with IFN-gamma/LPS for 24 hrs and measured 6 to 24 hrs after stimulation | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4401203 | B | Inhibition of ABHD12 in PMA-differentiated human THP1 cells assessed as increase in TNF-alpha production at 1 uM treated simultaneously with IFN-gamma/LPS for 24 hrs and measured 6 to 24 hrs after stimulation | Homo sapiens | 1 | assay format | Scientific Literature |
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