# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA961557 | B | Inhibition of human sFRP1 expressed in human U2OS assessed as fold induction in luciferase activity at 15 uM by TCF-luciferase reporter gene assay relative to control | Homo sapiens | 11 | ALA1151763 | assay format | Scientific Literature | |
2. | ALA961558 | B | Inhibition of human sFRP1 expressed in human U2OS assessed as fold induction in luciferase activity at 30 uM by TCF-luciferase reporter gene assay relative to control | Homo sapiens | 2 | ALA1151763 | assay format | Scientific Literature | |
3. | ALA961559 | B | Inhibition of human sFRP1 expressed in human U2OS assessed as luciferase activity by TCF-luciferase reporter gene assay | Homo sapiens | 4 | ALA1151763 | assay format | Scientific Literature | |
4. | ALA961568 | B | Binding affinity to human sFRP1 by fluorescence spectroscopy | Homo sapiens | 1 | ALA1151763 | single protein format | Scientific Literature | |
5. | ALA1011781 | B | Binding affinity to human purified SARP2 by fluorescent polarization assay | Homo sapiens | 31 | ALA1139350 | single protein format | Scientific Literature | |
6. | ALA1041726 | B | Inhibition of human SFRP1 transfected in human U20S cells by TCF-luciferase reporter gene assay | Homo sapiens | 1 | ALA1156102 | cell-based format | Scientific Literature | |
7. | ALA1041727 | B | Inhibition of human SFRP1 transfected in human U20S cells at 15 uM by TCF-luciferase reporter gene assay relative to control | Homo sapiens | 20 | ALA1156102 | cell-based format | Scientific Literature | |
8. | ALA1041728 | B | Inhibition of human SFRP1 transfected in human U20S cells at 30 uM by TCF-luciferase reporter gene assay relative to control | Homo sapiens | 5 | ALA1156102 | cell-based format | Scientific Literature | |
9. | ALA1041729 | B | Inhibition of human SFRP1 | Homo sapiens | 1 | ALA1156102 | single protein format | Scientific Literature | |
10. | ALA1041731 | B | Binding affinity to human SFRP1 by fluorescence spectroscopy | Homo sapiens | 1 | ALA1156102 | single protein format | Scientific Literature | |
11. | ALA1072833 | B | Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assay | Homo sapiens | 40 | ALA1157683 | single protein format | Scientific Literature | |
12. | ALA1072835 | B | Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 40 | ALA1157683 | cell-based format | Scientific Literature | |
13. | ALA1072836 | B | Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as drug level required for twofold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 40 | ALA1157683 | cell-based format | Scientific Literature | |
14. | ALA1072837 | B | Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as drug level required for fourfold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 38 | ALA1157683 | cell-based format | Scientific Literature | |
15. | ALA1072845 | B | Selectivity ratio of EC50 for human recombinant SFRP1 expressed in human U2OS cells to IC50 for human SFRP1 | Homo sapiens | 1 | ALA1157683 | cell-based format | Scientific Literature | |
16. | ALA1072846 | B | Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as drug level required for threefold increase in Wnt signaling after 16 to 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA1157683 | cell-based format | Scientific Literature | |
17. | ALA3293906 | B | Binding affinity to human recombinant sFRP1 by surface plasmon resonance assay | Homo sapiens | 3 | ALA3286317 | single protein format | Scientific Literature |