| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA811640 | B | Affinity towards RFC measured by the inhibition of [3H]MTX uptake | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 2. | ALA919632 | B | Inhibition of RFC-mediated [3H]MTX influx into human CCRF-CEM cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA1839674 | B | Inhibition of human RFC-mediated [3H]MTX uptake in chinese hamster PC43-10 cells at 10 uM after 2 mins relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA1006403 | B | Inhibition of human RFC-mediated [3H]MTX transport in Chinese hamster PC43-10 cells at 10 uM | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA1006404 | B | Inhibition of human RFC-mediated [3H]MTX transport expressed in Chinese hamster PC43-10 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA1067648 | B | Displacement of [3H]MTX from human RFC expressed in Chinese hamster PC43-10 cells at 10 uM | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA3106433 | B | Inhibition of human RFC expressed in chinese hamster PC43-10 cells assessed as reduction of [3H]MTX uptake at 10 uM after 48 hrs by scintillation counting analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3387469 | B | Inhibition of RFC (unknown origin) expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-blue cell viability assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 9. | ALA3412689 | B | Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA3632250 | B | Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 11. | ALA4194627 | B | Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viability after 96 hrs by Cell-Titer Blue assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 12. | ALA4309283 | B | Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth after 96 hrs by Cell-Titer Blue assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 13. | ALA4309288 | B | Binding affinity to human RFC2 expressed in human HeLa R1-11 cells assessed as antiproliferative activity measured as reduction in cell growth after 96 hrs by Cell-Titer Blue assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 14. | ALA4309293 | B | Inhibition of human RFC2 expressed in human HeLa R1-11 cells assessed as reduction in [3H]MTX uptake at pH 7.2 at 10 uM measured over 2 mins relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 15. | ALA4309324 | B | Inhibition of human RFC2 expressed in human HeLa R1-11 cells assessed as reduction in [3H]MTX uptake at pH 7.2 at 1 uM measured over 2 mins relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 16. | ALA4410579 | B | Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth after 96 hrs by Cell-Titer Blue assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 17. | ALA4432141 | B | Inhibition of human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viability after 96 hrs by Cell-Titer Blue fluorescence analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 18. | ALA4714596 | B | Inhibition of human RFC expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in cell proliferation after 96 hrs by CellTiter-blue assay | Homo sapiens | 8 | cell-based format | Scientific Literature |
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