# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1004498 | B | Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as thermal shift by differential scanning fluorimetry in absence of cofactor | Homo sapiens | 14 | assay format | Scientific Literature | ||
2. | ALA1004499 | B | Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as thermal shift by differential scanning fluorimetry in presence of NADP+ | Homo sapiens | 14 | assay format | Scientific Literature | ||
3. | ALA1004500 | B | Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as thermal shift by differential scanning fluorimetry in presence of NADPH | Homo sapiens | 14 | assay format | Scientific Literature | ||
4. | ALA1004504 | B | Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation at 200 uM relative to isatin | Homo sapiens | 7 | assay format | Scientific Literature | ||
5. | ALA1004505 | B | Binding affinity to human recombinant carbonyl reductase 1 expressed in Escherichia coli assessed as NADPH oxidation using isatin as substrate | Homo sapiens | 7 | assay format | Scientific Literature | ||
6. | ALA1068736 | B | Noncompetitive inhibition of human recombinant CBR expressed in Escherichia coli BL21 (DE3) in presence of 10 uM NADPH and 10 to 200 uM menadione | Homo sapiens | 1 | assay format | Scientific Literature | ||
7. | ALA1068737 | B | Inhibition of CBR-mediated NADPH-dependent reduction of menadione to menadiol | 1 | single protein format | Scientific Literature | |||
8. | ALA1068739 | B | Activity at human recombinant CBR expressed in Escherichia coli BL21 (DE3) by spectrophotometry | Homo sapiens | 9 | assay format | Scientific Literature | ||
9. | ALA1068740 | B | Ratio of Kcat to Km for human recombinant CBR expressed in Escherichia coli BL21 (DE3) | Homo sapiens | 9 | assay format | Scientific Literature | ||
10. | ALA1068741 | B | Displacement of menadione from human recombinant CBR expressed in Escherichia coli BL21 (DE3) | Homo sapiens | 4 | assay format | Scientific Literature | ||
11. | ALA1068742 | B | Displacement of daunorubicin from human recombinant CBR expressed in Escherichia coli BL21 (DE3) | Homo sapiens | 4 | assay format | Scientific Literature | ||
12. | ALA1068743 | B | Noncompetitive inhibition of human recombinant CBR expressed in Escherichia coli BL21 (DE3) in presence of 50 uM NADPH and 10 to 250 uM menadione | Homo sapiens | 1 | assay format | Scientific Literature | ||
13. | ALA1068744 | B | Noncompetitive inhibition of human recombinant CBR expressed in Escherichia coli BL21 (DE3) in presence of 300 uM NADPH and 3 to 130 uM menadione | Homo sapiens | 1 | assay format | Scientific Literature | ||
14. | ALA1068745 | B | Noncompetitive inhibition of human recombinant CBR expressed in Escherichia coli BL21 (DE3) in presence of 50 uM menadione and 3 to 50 uM NADPH | Homo sapiens | 1 | assay format | Scientific Literature | ||
15. | ALA1068746 | B | Noncompetitive inhibition of human recombinant CBR expressed in Escherichia coli BL21 (DE3) in presence of 250 uM menadione and 3 to 50 uM NADPH | Homo sapiens | 1 | assay format | Scientific Literature | ||
16. | ALA1068747 | B | Noncompetitive inhibition of human recombinant CBR expressed in Escherichia coli BL21 (DE3) in presence of 10 uM NADPH and 20 to 250 uM menadione | Homo sapiens | 1 | assay format | Scientific Literature | ||
17. | ALA1068748 | B | Noncompetitive inhibition of human recombinant CBR expressed in Escherichia coli BL21 (DE3) in presence of 50 uM NADPH and 14 to 250 uM menadione | Homo sapiens | 1 | assay format | Scientific Literature | ||
18. | ALA1068749 | B | Noncompetitive inhibition of human recombinant CBR expressed in Escherichia coli BL21 (DE3) in presence of 300 uM NADPH and 16 to 250 uM menadione | Homo sapiens | 1 | assay format | Scientific Literature | ||
19. | ALA2184161 | B | Activity of human recombinant His6-tagged carbonyl reductase 1 expressed in Escherichia coli BL21(DE3) using menadione as substrate by Michaelis-Menten plot analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
20. | ALA2184163 | B | Activity of His-tagged carbonyl reductase 1 | 1 | single protein format | Scientific Literature |