# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA902174 | B | Activation of Nurr1 expressed in MN9D cells by luciferase reporter gene assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
2. | ALA902175 | B | Activation of Nurr1 expressed in MN9D cells by luciferase reporter gene assay relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
3. | ALA1961865 | B | Effect on NURR1(NR4A2) dependent reporter activity in HEK293 cells at 20 uM | 2 | cell-based format | Scientific Literature | |||
4. | ALA1015275 | B | Increase in transcriptional activity of Nurr1 ligand binding domain expressed in human Hep G2 cells co-transfected with Gal4-DBD by luciferase reporter gene assay | 2 | cell-based format | Scientific Literature | |||
5. | ALA1227067 | F | Agonist activity at nuclear orphan receptor Nurr1 expressed in human BGC823 cells co-transfected with fused GAL4-Nurr1(LBD) assessed as transactivation after 12 hrs by transactivation assay | 1 | cell-based format | Scientific Literature | |||
6. | ALA4369795 | B | Binding affinity to Nurr1 (unknown origin) by 1H-STD-NMR spectroscopy | Homo sapiens | 2 | single protein format | Scientific Literature | ||
7. | ALA4370881 | B | Agonist activity at full-length Gal4-fused NOT (unknown origin) expressed in CHO cells by luciferase reporter gene assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
8. | ALA4823492 | B | Agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity incubated for 12 to 14 hrs by hybrid reporter gene assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
9. | ALA4823493 | B | Agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as fold increase luciferase activity incubated for 12 to 14 hrs by hybrid reporter gene assay relative to control | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
10. | ALA4823494 | B | Agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity at 10 uM incubated for 12 to 14 hrs by hybrid reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA4823495 | B | Agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity at 30 uM incubated for 12 to 14 hrs by hybrid reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA4823496 | B | Agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity at 300 uM incubated for 12 to 14 hrs by hybrid reporter gene assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
13. | ALA4823497 | B | Agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity at 100 uM incubated for 12 to 14 hrs by hybrid reporter gene assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
14. | ALA4823498 | B | Agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity at 200 uM incubated for 12 to 14 hrs by hybrid reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA4823499 | B | Agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing renilla luciferase assessed as renilla luciferase activity up to 300 uM incubated for 12 to 14 hrs by hybrid reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
16. | ALA4823500 | B | Agonist activity at full length human Nurr1 monomer response element NBRE expressed in HEK293T cells co-expressing firefly luciferase assessed as firefly luciferase activity up to 100 uM incubated for 12 to 14 hrs by hybrid reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA4823501 | B | Agonist activity at full length human Nurr1 homodimer response element NurRE expressed in HEK293T cells co-expressing firefly luciferase assessed as firefly luciferase activity up to 100 uM incubated for 12 to 14 hrs by hybrid reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA4823503 | B | Induction of Nurr1-regulated gene expression in human T98G cells assessed as increase VAMT2 mRNA level incubated for 8 hrs by qRT-PCT analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA4823504 | B | Induction of Nurr1-regulated gene expression in human T98G cells assessed as increase tyrosine hydrolase mRNA level incubated for 8 hrs by qRT-PCT analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA4823505 | B | Agonist activity at human Nurr1 LBD assessed as increase in biotinylated NCoR1 recruitment measured after 1 hr by HT-FRET assay | Homo sapiens | 2 | single protein format | Scientific Literature |