# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1963971 | F | PubChem BioAssay. Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay. (Class of assay: confirmatory) | 344 | assay format | PubChem BioAssays | |||
2. | ALA949699 | B | Inhibition of GLI1 induced hedgehog signaling in mouse NIH3T3 cells | Mus musculus | 2 | cell-based format | Scientific Literature | ||
3. | ALA3215070 | F | PubChem BioAssay. SAR analysis of small molecule antagonists of Gli-SUFU in a luminescent reporter assay - Set 2. (Class of assay: confirmatory) | 28 | assay format | PubChem BioAssays | |||
4. | ALA3214840 | F | PubChem BioAssay. SAR analysis of small molecule antagonists of Gli-SUFU in a luminescent reporter assay - Set 1. (Class of assay: confirmatory) | 58 | assay format | PubChem BioAssays | |||
5. | ALA4273266 | B | Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay | Mus musculus | 16 | single protein format | Scientific Literature | ||
6. | ALA4273267 | B | Inhibition of Gli1 transcriptional activity in Smo-/- mouse embroyonic fibroblasts up to 20 uM after 24 hrs by renilla luciferase reporter gene assay | Mus musculus | 4 | single protein format | Scientific Literature | ||
7. | ALA4273279 | B | Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts up to 30 uM after 24 hrs by renilla luciferase reporter gene assay | Mus musculus | 1 | single protein format | Scientific Literature | ||
8. | ALA4615967 | B | Inhibition of GLI1 transcriptional activity in HH-responsive mouse NIH3T3 cells assessed as reduction in GLI1 protein expression at 5 uM incubated for 48 hrs in presence of SAG by Western blot analysis | Mus musculus | 23 | cell-based format | Scientific Literature | ||
9. | ALA4615968 | B | Inhibition of GLI1 transcriptional activity in HH-responsive mouse NIH3T3 cells assessed as reduction in SAG-induced luciferase activity at 5 uM incubated for 48 hrs by luciferase reporter gene assay relative to control | Mus musculus | 23 | cell-based format | Scientific Literature |