# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2032922 | F | Antagonist activity at rat TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced Ca2+ influx incubated 2.5 mins prior icilin induction by flash luminometry | Rattus norvegicus | 49 | cell-based format | Scientific Literature | ||
2. | ALA1036705 | F | Agonist activity at rat recombinant TRPM8 receptor expressed in HEK293 cells assessed as increase in intracellular calcium concentration by fluorimetric test | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
3. | ALA1036706 | F | Antagonist activity at rat recombinant TRPM8 receptor expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular calcium concentration at 200 uM preincubated for 5 mins before icilin treatment by fluorimetric test | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
4. | ALA1036707 | F | Antagonist activity at rat recombinant TRPM8 receptor expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular calcium concentration at 200 uM preincubated for 15 mins before icilin treatment by fluorimetric test | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
5. | ALA1112951 | F | Antagonist activity at rat TRMP8 receptor expressed in HEK293 cells assessed as icilin-induced calcium elevation | Rattus norvegicus | 22 | cell-based format | Scientific Literature | ||
6. | ALA1112952 | F | Antagonist activity at rat TRMP8 receptor expressed in HEK293 cells assessed as menthol-induced calcium elevation | Rattus norvegicus | 22 | cell-based format | Scientific Literature | ||
7. | ALA1655533 | F | Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of intracellular calcium accumulation at 0.2 uM by FLIPR assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
8. | ALA1825345 | F | Antagonist activity at rat recombinant TRPM8 receptor expressed in HEK293 cells assessed as inhibition of 0.25 uM icilin-induced stimulation of intracellular calcium level using Fluo4-AM dye based fluorimetric assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
9. | ALA1958510 | F | Antagonist activity at rat TRPM8 by calcium flux assay | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
10. | ALA2433968 | B | Antagonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed as inhibition of menthol-induced intracellular calcium influx preincubated for 5 mins followed by menthol challenge by Fluo-4-AM dye-based spectrofluorimetric analysis | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
11. | ALA2433969 | B | Antagonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium influx preincubated for 5 mins followed by icilin challenge by Fluo-4-AM dye-based spectrofluorimetric analysis | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
12. | ALA2433970 | B | Agonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed as induction of intracellular calcium influx by Fluo-4-AM dye-based spectrofluorimetric analysis | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
13. | ALA2433971 | B | Agonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed as induction of intracellular calcium influx by Fluo-4-AM dye-based spectrofluorimetric analysis relative to ionomycin | Rattus norvegicus | 17 | cell-based format | Scientific Literature | ||
14. | ALA2444319 | B | Antagonist activity at rat TRPM8 by 45Ca2+ uptake assay | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
15. | ALA2091727 | B | Activation of rat TRPM8 expressed in HEK293 cells assessed as stimulation of intracellular Ca2+ levels relative to 4 uM ionomycin | Rattus norvegicus | 35 | cell-based format | Scientific Literature | ||
16. | ALA2091728 | B | Activation of rat TRPM8 expressed in HEK293 cells assessed as stimulation of intracellular Ca2+ levels | Rattus norvegicus | 35 | cell-based format | Scientific Literature | ||
17. | ALA2091978 | B | Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 0.25 uM icilin-stimulated increase in intracellular Ca2+ levels | Rattus norvegicus | 35 | cell-based format | Scientific Literature | ||
18. | ALA2091979 | B | Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 20 uM menthol-stimulated increase in intracellular Ca2+ levels | Rattus norvegicus | 35 | cell-based format | Scientific Literature | ||
19. | ALA5253447 | F | Invivo antagonist activity at TRPM8 in po dosed rat assessed as shaking behaviour | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
20. | ALA3238730 | B | Antagonist activity at rat TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced Ca2+ influx incubated 2.5 mins prior to icilin challenge by luminometry | Rattus norvegicus | 28 | cell-based format | Scientific Literature |