# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2061689 | F | Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
2. | ALA2061690 | F | Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation at 10 uM after 30 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA2061691 | F | Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation at 1 uM after 30 mins by HTRF assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA2061692 | F | Agonist activity at human GPR119 receptor expressed in CHO-K1 cells assessed as cAMP accumulation after 30 mins by HTRF assay relative to AR231453 | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
5. | ALA2089826 | F | Agonist activity at human GPR119 receptor over expressed in HEK293S cells assessed as increase in cAMP level after 45 mins by HTRF assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
6. | ALA2089827 | F | Intrinsic activity at human GPR119 receptor over expressed in HEK293S cells assessed as increase in cAMP level after 45 mins by HTRF assay relative to oleoylethanolamide | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
7. | ALA2073375 | F | Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cAMP level incubated for 6 hrs by luciferase activity based luminometry | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
8. | ALA2073376 | F | Intrinsic activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cAMP level at 10 uM incubated for 6 hrs by luciferase activity based luminometry relative to 10 uM 2-(2-(4-bromophenyl)-6-methylpyrimidin-4-ylamino)ethanol | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
9. | ALA1953649 | F | Agonist activity at human GPR119 receptor assessed as cAMP production by HTRF assay | Homo sapiens | 31 | assay format | Scientific Literature | ||
10. | ALA1953651 | F | Intrinsic activity at human GPR119 receptor assessed as cAMP production by HTRF assay relative to AR231453 | Homo sapiens | 29 | single protein format | Scientific Literature | ||
11. | ALA1958723 | F | Agonist activity at human GPR119 expressed in HEK293 cells co-transfected with pCRE-Luc assessed as induction in cAMP level after 6 hrs by luciferase reporter gene assay relative to 10 uM of 2-{[2-(4-Bromophenyl)-6-methylpyrimidin-4-yl]amino}ethanol | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
12. | ALA1958724 | F | Agonist activity at human GPR119 expressed in HEK293 cells co-transfected with pCRE-Luc assessed as induction in cAMP level at 10 uM after 6 hrs by luciferase reporter gene assay relative to 10 uM of 2-{[2-(4-Bromophenyl)-6-methylpyrimidin-4-yl]amino}ethanol | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
13. | ALA1958725 | F | Agonist activity at human GPR119 expressed in HEK293 cells co-transfected with pCRE-Luc assessed as induction in cAMP level at 10 uM after 6 hrs by luciferase reporter gene assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
14. | ALA1958734 | F | Agonist activity at human GPR119 expressed in HEK293 cells co-transfected with pCRE-Luc assessed as induction in cAMP level after 6 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA2016217 | F | Agonist activity at human GPR119 receptor expressed in HEK293 cells assessed as cAMP accumulation after 45 mins by fluorescence assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
16. | ALA2014815 | F | Agonist activity at human GPR119 receptor expressed in HEK293 cells assessed as cAMP accumulation after 45 mins by fluorescence assay relative to oleoylethanolamide | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
17. | ALA2161676 | F | Agonist activity at human recombinant GPR119 expressed in HEK293 cells co-expressing pCRE-Luc at 10 uM after 6 hrs by cAMP reporter assay relative to 2-(2-(4-bromophenyl)-6-methylpyrimidin-4-ylamino)ethanol | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
18. | ALA2161677 | F | Agonist activity at human recombinant GPR119 expressed in HEK293 cells co-expressing pCRE-Luc assessed as concentration required to showing equipotent efficacy to 2-(2-(4-bromophenyl)-6-methylpyrimidin-4-ylamino)ethanol after 6 hrs by cAMP reporter assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
19. | ALA968033 | F | Agonist activity at GPR119 expressed in HEK293 cells assessed as cAMP level by flash plate assay | 9 | cell-based format | Scientific Literature | |||
20. | ALA968034 | F | Inverse agonist activity at GPR119 expressed in HEK293 cells assessed as cAMP level by flash plate assay | 5 | cell-based format | Scientific Literature |