# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2114876 | F | PubChem BioAssay. Late stage assay provider results from the probe development effort to identify inhibitors of diacylglycerol lipase, beta (DAGLb): LCMS-based biochemical dose response assay. (Class of assay: confirmatory) | Mus musculus | 2 | assay format | PubChem BioAssays | ||
2. | ALA2114878 | F | PubChem BioAssay. Late stage assay provider results from the probe development effort to identify inhibitors of diacylglycerol lipase, beta (DAGLb): fluorescence-based dose-response biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of DAGLb in vitro. (Class of assay: confirmatory) | Mus musculus | 4 | assay format | PubChem BioAssays | ||
3. | ALA962975 | B | Inhibition of DAGLbeta in mouse brain assessed as >15 average spectral count at 50 uM treated for 30 mins by ABPP-MudPIT assay | Mus musculus | 2 | tissue-based format | Scientific Literature | ||
4. | ALA962976 | B | Inhibition of DAGLbeta in mouse brain assessed as >15 average spectral count at 5 uM treated for 30 mins by ABPP-MudPIT assay | Mus musculus | 2 | tissue-based format | Scientific Literature | ||
5. | ALA3268198 | B | Inhibition of FP-rhodamine-labelled recombinant mouse DAGLbeta expressed in HEK293T cells at 100 nM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
6. | ALA3268595 | B | Inhibition of FP-rhodamine-labelled recombinant mouse DAGLbeta expressed in HEK293T cells at 10 uM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
7. | ALA3268606 | B | Inhibition of FP-rhodamine-labelled recombinant mouse DAGLbeta expressed in HEK293T cells at 1 uM preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins by gel-based competitive ABPP assay | Mus musculus | 9 | cell-based format | Scientific Literature | ||
8. | ALA3270617 | B | Inhibition of Daglb in mouse Neuro2a cells at 3 nM after 4 hrs by ABPP-SILAC assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
9. | ALA3879160 | B | Inhibition of HT-01 probe binding to recombinant mouse DAGLbeta expressed in HEK293T cell membrane proteomes preincubated for 30 mins followed by HT-01 probe addition measured after 30 mins by gel-based competitive activity based protein profiling assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
10. | ALA3879163 | B | Inhibition of recombinant mouse DAGLbeta expressed in HEK293T cell membranes using PNP butyrate as substrate by colorimetric assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
11. | ALA4427012 | B | Inhibition of full length 3' FLAG-tagged mouse DAGLbeta expressed in African green monkey COS7 cells using sn-1-stearoyl-[14C]-arachidonoyl-glycerol as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins by radiometric natural substrate assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
12. | ALA4427013 | B | Inhibition mouse DAGLbeta expressed in HEK293T cell membrane fractions using DAG as substrate preincubated for 30 mins followed by ABP HT01 probe addition measured after 30 mins in presence of probe by gel-based ABPP competition assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
13. | ALA4427015 | B | Inhibition of V-tagged mouse DAGLbeta expressed in HEK2934T cell membrane fractions using SAG as substrate assessed as accumulation of 2-AG preincubated for 30 mins followed by probe addition measured after 30 mins by LC-MS natural substrate assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
14. | ALA4427016 | B | Inhibition of mouse DAGLbeta expressed in HEK293T cell membranes using SAG as substrate preincubated for 30 mins followed by substrate addition by enzyme coupled natural substrate assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
15. | ALA4626928 | B | Inhibition of mouse brain membrane DAGLbeta assessed as enzyme remaining activity at 10 uM preincubated for 30 mins followed by MB064 or FP-TAMRA addition and measured after 15 mins by SDS-PAGE based ABPP analysis relative to control | Mus musculus | 1 | cell membrane format | Scientific Literature |