| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2050324 | B | Inhibition of histamine H4 receptor-mediated chemotaxis in mouse bone marrow cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA1921331 | B | Displacement of [3H]-histamine from mouse H4R expressed in HEK293T cells | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA1919819 | F | Partial agonist activity at mouse H4R expressed in HEK293T cells assessed as reversal of forskolin-induced cAMP production by CRE-beta-lactamase reporter gene assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA1936570 | B | Displacement of [3H]histamine from mouse H4R | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 5. | ALA948408 | F | Antagonist activity at mouse histamine H4 receptor assessed as inhibition of histamine-induced intracellular calcium level by FLIPR | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA986305 | F | Antagonist activity at mouse histamine H4 receptor expressed in HEK293 cells assessed as inhibition of histamine-induced intracellular calcium elevation by FLIPR assay | Mus musculus | 10 | cell-based format | Scientific Literature | ||
| 7. | ALA986306 | F | Antagonist activity at mouse histamine H4 receptor expressed in HEK293 cells assessed as inhibition of histamine-induced intracellular calcium elevation by FLIPR assay relative to histamine | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA1028280 | F | Antagonist activity at mouse histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1028281 | F | Agonist activity at mouse histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA1028282 | F | Agonist activity at mouse histamine H4 receptor expressed in HEK293 cells coexpressing Gqi5 protein assessed as calcium flux by FLIPR assay relative to histamine | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA1116872 | F | Antagonist activity at mouse histamine H4 receptor assessed as decrease in intracellular calcium by FLIPR | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA1117994 | B | Displacement of [3H]histamine from mouse recombinant histamine H4 receptor | Mus musculus | 3 | single protein format | Scientific Literature | ||
| 13. | ALA1117996 | F | Antagonist activity at mouse histamine H4 receptor in SK-N-MC cells assessed as inhibition of forskolin-stimulated cAMP release preincubated for 10 mins before forskolin challenge | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA1117997 | F | Intrinsic activity at mouse histamine H4 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP responsive element-beta-galactosidase activity after 6 hrs by colorimetric cAMP assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA1117999 | F | Antagonist activity at mouse histamine H4 receptor in SK-N-MC cells assessed as ratio of compound EC50 to histamine EC50 | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA1638856 | F | Agonist activity at mouse histamine H4 receptor | Mus musculus | 1 | assay format | Scientific Literature | ||
| 17. | ALA1639031 | B | Binding affinity to mouse histamine H4 receptor expressed in human SK-N-MC cells by radioligand displacement assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA1639032 | F | Agonist activity at mouse histamine H4 receptor by luciferase reporter gene assay | Mus musculus | 4 | assay format | Scientific Literature | ||
| 19. | ALA1639033 | F | Agonist activity at mouse histamine H4 receptor by luciferase reporter gene assay relative to histamine | Mus musculus | 4 | assay format | Scientific Literature | ||
| 20. | ALA2379697 | B | Binding affinity to mouse histamine H4 receptor | Mus musculus | 5 | single protein format | Scientific Literature |
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