| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2045705 | B | Inhibition of mPGES1 in IL-1beta-stimulated human A549 cell assessed as inhibition of PGE2 production preincubated for 15 mins before substrate addition by RP-HPLC method | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 2. | ALA2045706 | B | Inhibition of mPGES1 in IL-1beta-stimulated human A549 cell assessed as remaining activity measuring of PGE2 level at 10 uM preincubated for 15 mins before substrate addition by RP-HPLC method | Homo sapiens | 11 | single protein format | Scientific Literature | ||
| 3. | ALA2050885 | B | Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 4. | ALA2050886 | B | Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA2050892 | B | Inhibition of mPGES-1 in IL1beta and TNFalpha-stimulated human HeLa cells assessed as PGE2 level after 24 hrs by LC-MS/MS analysis | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA2050894 | B | Inhibition of mPGES-1 in IL1beta and TNFalpha-stimulated human HeLa cells assessed as PGE2 level at 1 uM after 24 hrs by LC-MS/MS analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA2051003 | B | Inhibition of human recombinant mPGES-1 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA2051005 | B | Inhibition of mPGES-1 in IL1beta and TNFalpha-stimulated human HeLa cells assessed as PGE2 level at 10 uM after 24 hrs by LC-MS/MS analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA2072654 | B | Inhibition of mPGES-1-mediated PGE2 formation in IL-1beta-stimulated human A549 cells at 10 uM preincubated for 10 mins measured after 1 min by RP-HPLC analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2072655 | B | Inhibition of mPGES-1-mediated PGE2 formation in IL-1beta-stimulated human A549 cells preincubated for 10 mins measured after 1 min by RP-HPLC analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA1832706 | B | Inhibition of microsomal PGES | 3 | assay format | Scientific Literature | |||
| 12. | ALA1832707 | B | Inhibition of human recombinant microsomal PGES-1 expressed in freestyle 293-f cells assessed as conversion of PGH2 to PGE2 at 10 uM after 15 mins by enzyme immunoassay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 13. | ALA1832708 | B | Inhibition of human recombinant microsomal PGES-1 expressed in freestyle 293-f cells assessed as conversion of PGH2 to PGE2 after 15 mins by enzyme immunoassay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA1936279 | B | Inhibition of mPGES-1 in human A549 cell microsomes assessed as conversion of PGH2 into PGE2 at 3.3 uM at 0 degC after 5 mins by HPLC-UV analysis | Homo sapiens | 17 | microsome format | Scientific Literature | ||
| 15. | ALA1936306 | B | Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 1 uM at 20 degC after 5 mins by HPLC-UV analysis | Homo sapiens | 46 | single protein format | Scientific Literature | ||
| 16. | ALA1936307 | B | Inhibition of mPGES-1 in human A549 cell microsomes assessed as conversion of PGH2 into PGE2 at 0 degC after 5 mins by HPLC-UV analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 17. | ALA1936308 | B | Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 18. | ALA1936309 | B | Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 10 uM at 20 degC after 5 mins by HPLC-UV analysis in presence of 0.1% Triton X-100 | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 19. | ALA1936310 | B | Inhibition of mPGES-1 | 3 | single protein format | Scientific Literature | |||
| 20. | ALA1938076 | B | Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production at 10 uM after 60 mins by HTRF assay | Homo sapiens | 9 | cell-based format | Scientific Literature |
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