# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1011549 | B | Binding affinity to Hec1 in human HeLa cell extract by affinity pulldown assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA1011556 | B | Inhibition of Hec1/Nek2 complex in human Hela cells assessed as mitotic abnormality with multipolar spindle configuration at 3.75 uM after 24 hrs by immuno-fluorescent staining | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA1011560 | B | Inhibition of Hec1/Nek2 complex in human Hela cells assessed as mitotic abnormality with multipolar spindle configuration at 6.25 uM after 24 hrs by immuno-fluorescent staining | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA1011561 | B | Inhibition of Hec1/Nek2 complex in human Hela cells assessed as mitotic abnormality with multipolar spindle configuration at 25 uM after 24 hrs by immuno-fluorescent staining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA3268051 | B | Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as reduction in coimmunoprecipitated Hec1 level at 100 nM after 16 hrs by co-immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA3268052 | B | Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as induction of Nek2 degradation after 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA3268053 | B | Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as induction of Nek2 degradation at 10 nM after 24 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA3268054 | B | Inhibition of Hec1/Nek2 interaction in human MDA-MB-468 cells assessed as reduction in Hec1 level at 100 nM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA3268055 | B | Inhibition of Hec1/Nek2 interaction in human MDA-MB-468 cells assessed as induction of Nek2 degradation at 100 nM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA3268056 | B | Inhibition of Hec1/Nek2 interaction in human MDA-MB-468 cells assessed as induction of Nek2 degradation at 100 nM by western blot analysis in presence of 500 nM proteasome inhibition MG132 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA3268057 | B | Inhibition of Hec1/Nek2 interaction in human K562 cells assessed as reduction in coimmunoprecipitated Hec1 level at 100 nM after 16 hrs by co-immunoprecipitation assay in presence of 500 nM proteasome inhibitor MG132 | Homo sapiens | 1 | cell-based format | Scientific Literature |