| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2154132 | B | Inhibition of rat delta-5 desaturase activity expressed in human HEpG2 cells | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA1012735 | B | Inhibition of rat microsomal Delta-5-desaturase | Rattus norvegicus | 8 | assay format | Scientific Literature | ||
| 3. | ALA1044844 | B | Inhibition of stearoyl-CoA delta5 desaturase in rat microsome | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 4. | ALA1272961 | B | Inhibition of rat Delta(5) fatty acid desaturase by cell based assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1272963 | B | Inhibition of Delta(5) fatty acid desaturase in freshly isolated rat hepatocytes | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2320319 | B | Inhibition of delta6 desaturase in Sprague-Dawley rat liver microsome using cis,cis-9,12-octadecadienoic acid substrate at 10 uM | Rattus norvegicus | 30 | microsome format | Scientific Literature | ||
| 7. | ALA2320320 | B | Inhibition of delta5 desaturase in Sprague-Dawley rat liver microsome at 10 uM | Rattus norvegicus | 30 | microsome format | Scientific Literature | ||
| 8. | ALA3396836 | B | Inhibition of delta5 desaturase in Sprague-Dawley rat liver microsome at 10 uM by thin layer chromatography method | Rattus norvegicus | 23 | microsome format | Scientific Literature | ||
| 9. | ALA4026559 | B | Displacement of [3H]T-3364366 from D5D in rat liver microsomal membrane preincubated for 15 mins followed by radioligand addition measured after 150 mins by TopCount microscintillation counting assay | Rattus norvegicus | 21 | cell membrane format | Scientific Literature | ||
| 10. | ALA4433171 | B | Inhibition of D5D in Sprague-Dawley rat liver microsomes using [14C]DGLA as substrate preincubated for 5 mins measured after 120 mins | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 11. | ALA4433175 | B | Inhibition of D5D in rat RLN10 cells using [14C]DGLA as substrate preincubated for 30 mins followed by substrate addition measured after 3 hrs | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4433176 | B | Binding affinity to D5D in Sprague-Dawley rat liver microsomes after 150 mins by liquid scintillation counting | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 13. | ALA4433177 | B | Binding affinity to D5D in Sprague-Dawley rat liver microsomes at 1.2 to 20 nM measured up to 2.5 hrs by liquid scintillation counting | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 14. | ALA4433178 | B | Displacement of [3H]T-3364366 from D5D in Sprague-Dawley rat liver microsomes after 150 mins by liquid scintillation counting | Rattus norvegicus | 4 | microsome format | Scientific Literature | ||
| 15. | ALA4433179 | B | Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes assessed as compound bound to protein at 6 nM preincubated for 150 mins followed by 2 fold dilution by 10 uM of T-3364366 measured after 21 hrs by liquid scintillation counting relative to control | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 16. | ALA4433180 | B | Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes assessed as dissociation half life at 6 nM preincubated for 150 mins followed by 2 fold dilution by 10 uM of T-3364366 by liquid scintillation counting | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 17. | ALA4433181 | B | Reversible binding affinity to D5D in Sprague-Dawley rat liver microsomes after 150 mins in presence of trichloroacetate by liquid scintillation counting | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 18. | ALA4433193 | B | Displacement of [3H]T-3364366 from D5D in Sprague-Dawley rat liver microsomes at high concentrations after 150 mins by liquid scintillation counting | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 19. | ALA4433194 | B | Binding affinity to D5D in Sprague-Dawley rat liver microsomes at 1.2 to 20 nM measured after 2.5 hrs by liquid scintillation counting | Rattus norvegicus | 1 | microsome format | Scientific Literature |
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