# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1027322 | B | Inhibition of human GST-fused histone acetyltransferase CBP in U937 cell nuclear extracts assessed as remaining enzyme activity at 50 uM | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
2. | ALA1051186 | B | Binding affinity to histidine tagged KIX domain of CREB-binding protein by fluorescence polarization assay | 5 | single protein format | Scientific Literature | |||
3. | ALA1051187 | B | Binding affinity to histidine tagged KIX domain of CREB-binding protein expressed in Escherichia coli by affinity purification assay | 2 | assay format | Scientific Literature | |||
4. | ALA1614162 | F | PUBCHEM_BIOASSAY: Cell Viability - CRE-beta lactamase CHO cell - 24 hr assay. (Class of assay: confirmatory) [Related pubchem assays: 662 ] | Homo sapiens | 11 | cell-based format | PubChem BioAssays | ||
5. | ALA1614333 | F | PUBCHEM_BIOASSAY: Cell Viability - CRE-beta lactamase CHO cell - 40 hr assay. (Class of assay: confirmatory) [Related pubchem assays: 662 ] | Homo sapiens | 33 | cell-based format | PubChem BioAssays | ||
6. | ALA1614040 | F | PUBCHEM_BIOASSAY: Confirmation Concentration-Response Assay for Cell signaling CRE-BLA (Fsk stim) - HEK293 CREB Luciferase. (Class of assay: confirmatory) [Related pubchem assays: 662 ] | Homo sapiens | 107 | assay format | PubChem BioAssays | ||
7. | ALA1614026 | F | PUBCHEM_BIOASSAY: Confirmation Concentration-Response Assay for Cell signaling CRE-BLA (Fsk stim). (Class of assay: confirmatory) [Related pubchem assays: 662 ] | Homo sapiens | 92 | assay format | PubChem BioAssays | ||
8. | ALA1798474 | B | Inhibition of human recombinant KAT3A expressed in Escherichia coli BL21 using histone H4 peptide as substrate at 50 uM after 2 hrs relative to control | Homo sapiens | 19 | assay format | Scientific Literature | ||
9. | ALA1832848 | B | Binding affinity to CREBBP assessed as change in melting temperature at 100 uM by differential scanning fluorimetry | 9 | single protein format | Scientific Literature | |||
10. | ALA1832993 | B | Displacement of H3K56Ac from human CREBBP by peptide displacement assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
11. | ALA1832999 | B | Inhibition of CREBBP | 1 | single protein format | Scientific Literature | |||
12. | ALA1958933 | B | Binding affinity to CREBBP assessed as change in melting temperature at 100 uM by protein stability shift assay | 12 | single protein format | Scientific Literature | |||
13. | ALA1958942 | B | Binding affinity to CREBBP assessed as change in melting temperature at 10 uM by protein stability shift assay | 6 | single protein format | Scientific Literature | |||
14. | ALA1958570 | B | Displacement of acetylated histone peptide from CREBBP by luminescence proximity homogenous assay | 1 | single protein format | Scientific Literature | |||
15. | ALA2156121 | B | Binding affinity to CREBBP by isothermal titration calorimetric analysis | 1 | single protein format | Scientific Literature | |||
16. | ALA2187426 | B | Inhibition of His6FLAG-tagged CREBBP expressed in Escherichia coli assessed as change in melting temperature at 100 uM by thermal shift assay | 2 | assay format | Scientific Literature | |||
17. | ALA2183679 | B | Binding affinity to CREBBP assessed as change in melting temperature at 10 uM by thermal shift assay | 1 | single protein format | Scientific Literature | |||
18. | ALA2183680 | B | Binding affinity to CREBBP by SPR method | 1 | single protein format | Scientific Literature | |||
19. | ALA2344877 | B | Binding affinity to CREBBP bromodomain (unknown origin) using H3K56Ac peptide by amplified luminescent proximity homogeneous assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
20. | ALA3089620 | B | Displacement of fluorescein-labeled MS226 from recombinant human CBP bromodomain after 1 hr by fluorescence anisotropy assay | Homo sapiens | 4 | single protein format | Scientific Literature |