# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3630667 | Binding | Inhibition of HPK1 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | single protein format | Scientific Literature | |
2. | ALA3748214 | Binding | Inhibition of human HPK1 using MBP as substrate | Homo sapiens | 1 | ALA3745707 | single protein format | Scientific Literature | |
3. | ALA3802054 | Binding | Inhibition of full length wild type human HPK1 expressed in bacterial system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3797029 | assay format | Scientific Literature | |
4. | ALA1166019 | Binding | Inhibition of HPK1 at 1 uM | 7 | ALA1165965 | single protein format | Scientific Literature | ||
5. | ALA1174450 | Binding | Inhibition of HPK1 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
6. | ALA1244371 | Binding | Inhibition of MAP4K1 | 1 | ALA1240341 | single protein format | Scientific Literature | ||
7. | ALA1244866 | Binding | Binding affinity to HPK1 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
8. | ALA1827562 | Binding | Activity of HPK1 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
9. | ALA1838170 | Binding | Inhibition of human HPK1 in HL60 cells lysate at 10 uM using post probe-labeling by LC-MS/MS analysis relative to control | Homo sapiens | 5 | ALA1833925 | cell-based format | Scientific Literature | |
10. | ALA4351891 | Binding | Inhibition of recombinant human HPK1 (1 to 346 residues) at 10 uM using myelin basic protein as substrate measured after 40 mins in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 1 | ALA4350961 | single protein format | Scientific Literature | |
11. | ALA4352400 | Binding | Inhibition of human HPK1 at 10 uM using MBP as substrate in presence of [gamma-33P]-ATP | Homo sapiens | 1 | ALA4350963 | single protein format | Scientific Literature | |
12. | ALA4357922 | Binding | Binding affinity to wild-type human full length HPK1 (M1 to R799 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4354843 | assay format | Scientific Literature | |
13. | ALA1908513 | Binding | Binding constant for HPK1 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
14. | ALA1944037 | Binding | Inhibition of MAP4K1 at 1 uM | 1 | ALA1938300 | single protein format | Scientific Literature | ||
15. | ALA1942768 | Binding | Inhibition of human HPK1 in HL-60 cells lysate assessed as reduction of labeling of acyl-phosphate ATP probe at 100 nM | Homo sapiens | 4 | ALA1938230 | cell-based format | Scientific Literature | |
16. | ALA1645808 | Binding | Inhibition of MAP4K1 at 1 uM | 1 | ALA1641548 | single protein format | Scientific Literature | ||
17. | ALA1061176 | Binding | Binding constant for MAP4K1 kinase domain | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
18. | ALA1049115 | Binding | Inhibition of MAP4K1 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
19. | ALA992627 | Binding | Binding affinity to human HPK1 at 10 uM relative to control | Homo sapiens | 17 | ALA1151712 | single protein format | Scientific Literature | |
20. | ALA987172 | Binding | Inhibition of MAP4K1 at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature |