# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA939001 | Binding | Inhibition of rat recombinant DAAO expressed in sf9 insect cells assessed as degradation of D-serine by fluorescence assay | Rattus norvegicus | 27 | ALA1136932 | cell-based format | Scientific Literature | |
2. | ALA2327670 | Binding | Inhibition of rat liver DAO using putrescine as substrate after 1 hr by fluorometric assay | Rattus norvegicus | 1 | ALA2321785 | assay format | Scientific Literature | |
3. | ALA2343130 | Binding | Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysis | Rattus norvegicus | 20 | ALA2331290 | cell-based format | Scientific Literature | |
4. | ALA2378317 | Binding | Inhibition of DAAO in Sprague-Dawley lactating rat hypothalamus assessed as reduction in AMPA/NMDA ratio of excitatory postsynaptic currents in supraoptic nucleus neurons at 10 uM after 45 mins by whole-cell patch clamp assay (Rvb = 4.08 +/- 0.41) | Rattus norvegicus | 1 | ALA2375208 | tissue-based format | Scientific Literature | |
5. | ALA2378330 | Binding | Inhibition of DAAO in Sprague-Dawley virgin rat hypothalamus assessed as change in AMPA/NMDA ratio of excitatory postsynaptic currents in supraoptic nucleus neurons at 10 uM after 45 mins by whole-cell patch clamp assay (Rvb = 1.12 +/- 0.23) | Rattus norvegicus | 1 | ALA2375208 | tissue-based format | Scientific Literature | |
6. | ALA2378522 | Binding | Inhibition of rat DAO using [14C]-putrescine as substrate after 1 hr by scintillation counting analysis | Rattus norvegicus | 1 | ALA2375334 | single protein format | Scientific Literature | |
7. | ALA3807135 | Binding | Inhibition of rat spinal DAAO using D-alanine as substrate assessed as pyruvate production incubated for 60 mins by microplate reader analysis | Rattus norvegicus | 7 | ALA3804792 | single protein format | Scientific Literature |