# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA997151 | B | Inhibition of dynamin 2-mediated endocytosis internalization of Texas red-transferrin in human U2OS cells at 30 uM pretreated for 30 mins | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA997152 | B | Inhibition of dynamin 2-mediated endocytosis internalization of Texas red-transferrin in human U2OS cells at 20 uM pretreated for 30 mins | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA997153 | B | Inhibition of dynamin 2-mediated endocytosis internalization of Texas red-transferrin in human U2OS cells at 100 uM pretreated for 30 mins | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA1110055 | B | Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assay | 5 | cell-based format | Scientific Literature | |||
5. | ALA1110056 | B | Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisition and analysis system | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA1119289 | B | Inhibition of recombinant dynamin 2 expressed in Sf9 cells after 30 mins by malachite green method | 4 | cell-based format | Scientific Literature | |||
7. | ALA1119291 | B | Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisition and analysis system | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA2318140 | B | Inhibition of dyn2 in human U2OS cells assessed as clathrin-mediated endocytosis of Tfn after 30 mins | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
9. | ALA4001126 | B | Inhibition of phosphatidyl serine liposome-stimulated dynamin 2 GTPase activity (unknown origin) assessed as reduction orthophosphate release using GTP as substrate after 30 mins by malachite green reagent based colorimetric assay | Homo sapiens | 12 | single protein format | Scientific Literature | ||
10. | ALA4001128 | B | Inhibition of dynamin 2 in human U2OS cells assessed as reduction in clathrin-mediated endocytosis by measuring transferrin-A594 uptake preincubated for 30 mins followed by Tfn-A594 addition for 8 mins by DAPI staining based HTS assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
11. | ALA4421899 | B | Inhibition of Dynamin-2 in human lymphoblasts assessed as accumulation of clathrin coated pits at the plasma membrane incubated for 30 mins by electron microscopic analysis | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
12. | ALA4421900 | B | Inhibition of Dynamin-2 in human lymphoblasts incubated for 30 mins by electron microscopic analysis | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
13. | ALA4421901 | B | Ring stabilizer activity at Dynamin-2 in human lymphoblasts assessed as accumulation in all cells of clathrin coated pits with highly elongated necks incubated for 30 mins by electron microscopic analysis | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
14. | ALA4421902 | B | Ring stabilizer activity at Dynamin-2 in human lymphoblasts assessed as accumulation in all cells of clathrin coated pits with highly elongated necks encircled by electron dense rings incubated for 30 mins by electron microscopic analysis | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data |