# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA958165 | B | Inhibition of CCR9 | 1 | ALA1151747 | single protein format | Scientific Literature | ||
2. | ALA2184856 | F | Antagonist activity at CCR9 assessed as inhibition of CCL25-induced chemotaxis by cell based assay | 1 | ALA2176887 | cell-based format | Scientific Literature | ||
3. | ALA2184877 | B | Binding affinity to CCR9 | 1 | ALA2176887 | single protein format | Scientific Literature | ||
4. | ALA2328028 | B | Antagonist activity at CCR9 (unknown origin) assessed as inhibition of chemotaxis at 10 uM | Homo sapiens | 1 | ALA2321873 | single protein format | Scientific Literature | |
5. | ALA2328620 | F | Antagonist activity at CCR9 (unknown origin) assessed as inhibition of calcium flux at 10 uM | Homo sapiens | 1 | ALA2321873 | single protein format | Scientific Literature | |
6. | ALA2328640 | B | Binding affinity to CCR9 (unknown origin) at 10 uM by radioligand displacement assay | Homo sapiens | 1 | ALA2321873 | single protein format | Scientific Literature | |
7. | ALA3097210 | B | Inhibition of CCR9 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA3091329 | single protein format | Scientific Literature | |
8. | ALA3607106 | F | Antagonist activity at CCR9 receptor (unknown origin) assessed as inhibition of TECK-induced calcium mobilization incubated for 10 mins prior to TECK induction | Homo sapiens | 34 | ALA3603812 | single protein format | Scientific Literature | |
9. | ALA3607107 | B | Antagonist activity at CCR9 receptor (unknown origin) by buffer chemotaxis assay | Homo sapiens | 15 | ALA3603812 | single protein format | Scientific Literature | |
10. | ALA3607108 | B | Antagonist activity at CCR9 receptor (unknown origin) by serum chemotaxis assay | Homo sapiens | 2 | ALA3603812 | single protein format | Scientific Literature | |
11. | ALA3721192 | F | Antagonist activity against CCR9 in human MOLT4 cells assessed as inhibition of human recombinant TECK-induced calcium response pre-treated before TECK stimulation by Flou-4-AM dye based FLIPR assay | Homo sapiens | 193 | ALA3714750 | cell-based format | Patent Bioactivity Data | |
12. | ALA3721193 | F | Antagonist activity against CCR9 in human MOLT4 cells assessed as inhibition of human recombinant TECK-induced cell migration pre-treated for 15 mins before TECK stimulation for 150 mins by fluorescence based assay | Homo sapiens | 193 | ALA3714750 | cell-based format | Patent Bioactivity Data | |
13. | ALA3721196 | F | Antagonist activity against CCR9 in human MOLT4 cells assessed as inhibition of human recombinant TECK-induced calcium response pre-treated before TECK stimulation by Flou-4-AM dye based FLIPR assay | Homo sapiens | 104 | ALA3714744 | cell-based format | Patent Bioactivity Data | |
14. | ALA3721199 | F | Antagonist activity against CCR9 in human MOLT4 cells assessed as inhibition of human recombinant TECK-induced cell migration pre-treated for 15 mins before TECK stimulation for 150 mins by fluorescence based assay | Homo sapiens | 104 | ALA3714744 | cell-based format | Patent Bioactivity Data | |
15. | ALA3801235 | F | Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubated for 1 hr followed CCL25 addition by FLIPR assay | Homo sapiens | 68 | ALA3797083 | cell-based format | Scientific Literature | |
16. | ALA3801236 | F | Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubated for 1 hr followed CCL25 addition by FLIPR assay | Homo sapiens | 14 | ALA3797083 | cell-based format | Scientific Literature | |
17. | ALA3801237 | B | Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCl25-mediated cell migration preincubated for 30 mins followed CCL25 addition incubated for 2 hrs by ChemoTx plate system | Homo sapiens | 14 | ALA3797083 | cell-based format | Scientific Literature | |
18. | ALA3815306 | F | Antagonist activity at CCR9 (unknown origin) assessed as inhibition of TECK-stimulated calcium mobilization preincubated for 10 mins followed by agonist addition measured for 90 sec by fluo-8 dye-based FLIPR assay | Homo sapiens | 21 | ALA3813597 | single protein format | Scientific Literature | |
19. | ALA3815318 | B | Inhibition of CCR9-mediated chemotaxis in human MOLT4 cells preincubated for 10 mins followed by TECK addition in presence of 0.1% BSA measured after 2 hrs | Homo sapiens | 7 | ALA3813597 | cell-based format | Scientific Literature | |
20. | ALA3815319 | F | Antagonist activity at CCR9 (unknown origin) assessed as inhibition of TECK-stimulated calcium mobilization at 3 uM preincubated for 10 mins followed by agonist addition measured for 90 sec by fluo-8 dye-based FLIPR assay | Homo sapiens | 1 | ALA3813597 | single protein format | Scientific Literature |