| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2025842 | B | Displacement of 5-carboxyfluorescein-labeled GpYLVLDKW from the STAT5b-SH2 domain after 15 mins by fluorescent polarization assay | 10 | single protein format | Scientific Literature | |||
| 2. | ALA1013508 | B | Inhibition of IL2-induced STAT5B phosphorylation in human YT cells at 30 ng/ml by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA1029439 | B | Inhibition of STAT5b SH2 domain at 200 uM | 7 | single protein format | Scientific Literature | |||
| 4. | ALA1043447 | B | Inhibition of erythropoietin-stimulated STAT5 expressed in human U2OS cells | 3 | cell-based format | Scientific Literature | |||
| 5. | ALA1695681 | B | Inhibition of STAT5b DNA binding activity in IL-6 stimulated human MDA-MB-468 cells at 50 uM by transcription factor ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3390778 | B | Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assay | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 7. | ALA3390780 | B | Binding affinity to full-length His-tagged STAT5B (unknown origin) by surface plasmon resonance assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4010008 | B | Binding affinity to STAT5B (unknown origin) after 30 mins by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4055339 | B | Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addition after 1 hr by fluorescence polarization assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 10. | ALA4055867 | B | Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to STAT5B SH2 domain (unknown origin) pre-incubated for 1 hr before fluorescent-labelled peptide addition by fluorescence polarization assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 11. | ALA4357304 | B | Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated for 12 hrs by fluorescence polarization assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 12. | ALA4357324 | B | Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) assessed as change in melting temperature by CETSA method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4362122 | B | Effect on STAT5b at Y699 phosphorylation level in human NCI-H1975 incubated for 12 hrs by human phosphokinase proteome profiler array relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4362160 | B | Effect on STAT5b at Y699 phosphorylation level in human NCI-H1975 incubated for 12 hrs by human phosphokinase proteome profiler array relative to beta-catenin | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4401664 | B | Inhibition of STAT5b phosphorylation at Y694 in human MV4-11 cells at 10 uM after 5 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4715466 | B | Binding affinity to human recombinant STAT5B assessed as dissociation constant incubated for 15 mins by biolayer interferometry | Homo sapiens | 1 | single protein format | Scientific Literature |
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