# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1015294 | F | Agonist activity at human MrgX2 receptor | Homo sapiens | 7 | assay format | Scientific Literature | ||
2. | ALA1015295 | F | Agonist activity at human MrgX2 receptor at 10 uM relative to cortistatin-14 | Homo sapiens | 12 | assay format | Scientific Literature | ||
3. | ALA3721005 | B | Activation of human MrgX2 receptor expressed in NIH/3T3 cells incubated for 5 days by beta-galactosidase reporter gene assay | Homo sapiens | 10 | cell-based format | Patent Bioactivity Data | ||
4. | ALA3721006 | B | Activation of human MrgX2 receptor expressed in NIH/3T3 cells incubated for 5 days by beta-galactosidase reporter gene assay relative to STIA | Homo sapiens | 10 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4613001 | B | Agonist activity at MRGPX2 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA4613002 | B | Agonist activity at MRGPX2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA4883536 | B | PRESTO-Tango GPCRome screening (MRGPRX2) | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | |||
8. | ALA4884583 | B | PRESTO-Tango concentration response assay | Homo sapiens | 2 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
9. | ALA4884584 | B | FLIPR assay | Homo sapiens | 2 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
10. | ALA5042033 | B | Positive allosteric modulator activity at human MRGPRX2 transfected in HEK293 cells at 5 uM in presence of C48/80 by Fluo-4 AM-based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA5126027 | F | Antagonist activity at human MRGPRX2 expressed in HEK293 cells co-expressing mouse Galpha15 assessed as inhibition of Cortistatin-14 induced Ca2+ mobilization preincubated for 30 mins followed by Cortistatin-14 addition by FLIPRtetra-calcium mobilization assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
12. | ALA5133297 | B | Agonistic activity at MRGPRX2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA5133299 | F | Agonist activity at MRGPRX2 (unknown origin) expressed in HEK293 cells assessed as induction of G(o) dissociation by measuring luminescent decay at 10 uM by NanoBiT-G-protein dissociation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA5133300 | F | Agonist activity at MRGPRX2 (unknown origin) expressed in HEK293 cells assessed as induction of G(o) dissociation by measuring luminescent decay at 32 uM by NanoBiT-G-protein dissociation assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA5141527 | F | Antagonist activity at MRGPRX2 (unknown origin) expressed in HEK293 cells assessed as inhibition of calcium mobilization at upto 10 uM | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
16. | ALA5145526 | F | Antagonist activity at MRGPRX2 (unknown origin) expressed in HEK293 cells assessed as inhibition of C48/80-induced Ca2+- mobilization | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA5210269 | B | Affinity On-target Cellular interaction (PRESTO-Tango concentration response assay (by the NIMH-PDSP)) EUB0000345a MRGPRX2 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library | ||
18. | ALA5210275 | B | Affinity On-target Cellular interaction (PRESTO-Tango concentration response assay (by the NIMH-PDSP)) EUB0000353a MRGPRX2 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library | ||
19. | ALA5214386 | B | Selectivity interaction (FLIPR assay) EUB0000345a MRGPRX2 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library | ||
20. | ALA5214421 | B | Selectivity interaction (FLIPR assay) EUB0000353a MRGPRX2 | Homo sapiens | 1 | single protein format | Literature data from EUbOPEN Chemogenomic Library |