# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA991397 | F | Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assay | Homo sapiens | 29 | ALA1143385 | cell-based format | Scientific Literature | |
2. | ALA1031335 | F | Intrinsic activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assay relative to BAM3200 | Homo sapiens | 14 | ALA1143385 | cell-based format | Scientific Literature | |
3. | ALA1015292 | F | Agonist activity at human MrgX1 receptor | Homo sapiens | 8 | ALA1153297 | assay format | Scientific Literature | |
4. | ALA1015293 | F | Agonist activity at human MrgX1 receptor at 10 uM relative to BAM22 | Homo sapiens | 12 | ALA1153297 | assay format | Scientific Literature | |
5. | ALA1015300 | F | Agonist activity at MrgX1 receptor by calcium mobilization assay | 1 | ALA1153297 | assay format | Scientific Literature | ||
6. | ALA1763646 | F | Antagonist activity at SNSR4 in human HEK293 cells by FLIPR assay | Homo sapiens | 16 | ALA1759871 | cell-based format | Scientific Literature | |
7. | ALA3388384 | B | Agonist activity at human MrgX1 transfected in HEK293 cells by FLIPR assay | Homo sapiens | 10 | ALA3351571 | cell-based format | Scientific Literature | |
8. | ALA3388387 | B | Agonist activity at human MrgX1 transfected in HEK293 cells at 2 uM by FLIPR assay | Homo sapiens | 1 | ALA3351571 | cell-based format | Scientific Literature | |
9. | ALA3388388 | B | Antagonist activity at human MrgX1 transfected in HEK293 cells by FLIPR assay | Homo sapiens | 2 | ALA3351571 | cell-based format | Scientific Literature | |
10. | ALA3388389 | B | Antagonist activity at human MrgX1 transfected in HEK293 cells at 200 uM by FLIPR assay | Homo sapiens | 2 | ALA3351571 | cell-based format | Scientific Literature | |
11. | ALA3721003 | B | Activation of human MrgX1 receptor expressed in NIH/3T3 cells incubated for 5 days by beta-galactosidase reporter gene assay | Homo sapiens | 10 | ALA3714739 | cell-based format | Patent Bioactivity Data | |
12. | ALA3721004 | B | Activation of human MrgX1 receptor expressed in NIH/3T3 cells incubated for 5 days by beta-galactosidase reporter gene assay relative to Bam22 | Homo sapiens | 10 | ALA3714739 | cell-based format | Patent Bioactivity Data | |
13. | ALA3721011 | F | Activation of human MrgX1 receptor expressed in CHOK1/HEK293 cells assessed as stimulation of intracellular calcium mobilization by Fura-2 dye based fluorescence assay | Homo sapiens | 4 | ALA3714739 | cell-based format | Patent Bioactivity Data | |
14. | ALA3721012 | F | Activation of human MrgX1 receptor expressed in CHOK1/HEK293 cells assessed as stimulation of intracellular calcium mobilization by Fura-2 dye based fluorescence assay relative to BAM22 | Homo sapiens | 4 | ALA3714739 | cell-based format | Patent Bioactivity Data | |
15. | ALA3734548 | F | Antagonist activity at MrgX1 (unknown origin) by beta-lactamase reporter gene assay | Homo sapiens | 16 | ALA3727359 | assay format | Patent Bioactivity Data | |
16. | ALA3734551 | B | Binding affinity to recombinant MrgX1 (unknown origin) by chromatography-based technique | Homo sapiens | 16 | ALA3727359 | single protein format | Patent Bioactivity Data | |
17. | ALA4337478 | B | Agonist activity at human MrgprX1 | Homo sapiens | 1 | ALA4334491 | single protein format | Scientific Literature | |
18. | ALA4337482 | B | Agonist activity at human MrgprX1 expressed in HEK293 cells incubated for 2 mins by Fluo4AM dye based FLIPR assay relative to BAM8-22 | Homo sapiens | 18 | ALA4334491 | cell-based format | Scientific Literature | |
19. | ALA4337483 | B | Agonist activity at human MrgprX1 expressed in HEK293 cells up to 100 uM incubated for 2 mins by Fluo4AM dye based FLIPR assay relative to BAM8-22 | Homo sapiens | 2 | ALA4334491 | cell-based format | Scientific Literature | |
20. | ALA4337484 | B | Agonist activity at human MrgprX1 expressed in HEK293 cells incubated for 2 mins by Fluo4AM dye based FLIPR assay | Homo sapiens | 20 | ALA4334491 | cell-based format | Scientific Literature |