# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1031407 | Binding | Inhibition of human GPR103 at 3 uM | Homo sapiens | 1 | ALA1142492 | single protein format | Scientific Literature | |
2. | ALA1804403 | Functional | Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization at 10' -12 to 10'-5 M after 2 mins by fluorometric analysis | Homo sapiens | 16 | ALA1800022 | cell-based format | Scientific Literature | |
3. | ALA1804404 | Functional | Antagonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as inhibition of 26RFa-induced calcium mobilization after 2 mins by fluorometric analysis | Homo sapiens | 14 | ALA1800022 | cell-based format | Scientific Literature | |
4. | ALA1804405 | Functional | Agonist activity at DYKDDDDK-flagged human GPR103 receptor expressed in CHO-K1 cells co-expressing G-protein alpha16 assessed as stimulation of calcium mobilization after 2 mins by fluorometric analysis | Homo sapiens | 42 | ALA1800022 | cell-based format | Scientific Literature | |
5. | ALA1839777 | Binding | Binding affinity to human GPR103 receptor at 10 uM by radioligand binding assay | Homo sapiens | 1 | ALA1833814 | single protein format | Scientific Literature | |
6. | ALA3368108 | Binding | Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assay | Homo sapiens | 14 | ALA3352699 | cell-based format | Scientific Literature | |
7. | ALA3368109 | Binding | Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation counting | Homo sapiens | 3 | ALA3352699 | cell-based format | Scientific Literature | |
8. | ALA3295521 | Functional | Antagonist activity at human GPR103 receptor assessed as inhibition of inositol-1-phosphate production by cell-based assay | Homo sapiens | 30 | ALA3286355 | cell-based format | Scientific Literature | |
9. | ALA3295522 | Binding | Displacement of [125I]-QRFP43 from human GPR103 receptor overexpressed in HEK membranes after 90 mins by liquid scintillation counting | Homo sapiens | 22 | ALA3286355 | cell membrane format | Scientific Literature | |
10. | ALA2167240 | Binding | Inhibition of human GPR103 receptor at 10 uM by radioligand displacement assay | Homo sapiens | 1 | ALA2163259 | single protein format | Scientific Literature | |
11. | ALA2174315 | Functional | Antagonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as inhibition of human 26RFa-induced increase in intracellular calcium level by fluorimetry | Homo sapiens | 14 | ALA2169738 | cell-based format | Scientific Literature | |
12. | ALA2174319 | Binding | Displacement of [125I]26RFa from human GPR103 expressed in HEK293 cells incubated for 1 h by gamma counter based method | Homo sapiens | 4 | ALA2169738 | cell-based format | Scientific Literature | |
13. | ALA2174320 | Functional | Agonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as increase in intracellular calcium level measured for 2 mins by fluorimetry | Homo sapiens | 18 | ALA2169738 | cell-based format | Scientific Literature | |
14. | ALA4276417 | Functional | Agonist activity at human QRFPR expressed in CHO cells co-expressing Galpha16 assessed as increase Ca2+ mobilization after 3 mins by Fluo-4 AM-based scanning fluorometery | Homo sapiens | 36 | ALA4270668 | cell-based format | Scientific Literature | |
15. | ALA4276418 | Functional | Antagonist activity at human QRFPR expressed in CHO cells co-expressing Galpha16 assessed as inhibition of 26RFa-induced Ca2+ mobilization preincubated for 15 mins followed by agonist addition measured after 3 mins by Fluo-4 AM-based scanning fluorometery | Homo sapiens | 35 | ALA4270668 | cell-based format | Scientific Literature | |
16. | ALA4276419 | Functional | Antagonist activity at human QRFPR expressed in CHO cells co-expressing Galpha16 assessed as inhibition of 26RFa-induced Ca2+ mobilization at 100 uM preincubated for 15 mins followed by agonist addition measured after 3 mins by Fluo-4 AM-based scanning fluorometery relative to 26RFa (20 to 26 residues) | Homo sapiens | 3 | ALA4270668 | cell-based format | Scientific Literature | |
17. | ALA4276420 | Functional | Antagonist activity at human QRFPR expressed in CHO cells co-expressing Galpha16 assessed as inhibition of 26RFa-induced Ca2+ mobilization at 10 uM preincubated for 30 mins followed by agonist addition measured after 3 mins by Fluo-4 AM-based scanning fluorometery | Homo sapiens | 2 | ALA4270668 | cell-based format | Scientific Literature | |
18. | ALA4772292 | Binding | Displacement of [125I]-43RFa from human QRFP receptor expressed in CHO cell membrane by TopCount scintillation counter method | Homo sapiens | 2 | ALA4765381 | cell membrane format | Scientific Literature | |
19. | ALA4882344 | Binding | GPR103 Eurofins-Panlabs selectivity data (BI) | Homo sapiens | 1 | ALA4507279 | single protein format | Donated Chemical Probes - SGC Frankfurt | |
20. | ALA4882394 | Binding | GPR103 Eurofins-Panlabs selectivity data (BI) | Homo sapiens | 1 | ALA4507280 | single protein format | Donated Chemical Probes - SGC Frankfurt |