| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA979111 | B | Inhibition of human recombinant soluble adenylyl cyclase | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 2. | ALA4839263 | B | Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay | Homo sapiens | 22 | single protein format | Scientific Literature | ||
| 3. | ALA4839264 | B | Potency index, ratio of IC50 for LRE1 to IC50 for test compound for inhibition of human soluble adenylyl cyclase | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4839265 | B | Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mins with test compounds in the presence of IBMX by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA5218087 | B | Inhibition of human ADCY10 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA5218088 | B | Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as substrate by sequential chromatographic analysis | Homo sapiens | 31 | single protein format | Scientific Literature | ||
| 7. | ALA5218089 | B | Inhibition of human ADCY10 assessed as cAMP accumulation at 500 uM preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as substrate by sequential chromatographic analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA5218091 | B | Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation constant and measured for 600 sec by SPR analysis | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 9. | ALA5218092 | B | Binding affinity to human recombinant His-tagged ADCY10 assessed as residence time and measured for 600 sec by SPR analysis | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 10. | ALA5218093 | B | Binding affinity to human recombinant GST-tagged ADCY10 assessed as residence time by cAMP level preincubated for 15 mins followed by substrate addition and measured after 1 hr using alpha-32P ATP as substrate by sequential chromatographic analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 11. | ALA5218115 | B | Binding affinity to human recombinant His-tagged ADCY10 assessed as association rate constant (kon) and measured for 120 sec by SPR analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 12. | ALA5218116 | B | Binding affinity to human recombinant His-tagged ADCY10 assessed as dissociation rate constant (koff) and measured for 600 sec by SPR analysis | Homo sapiens | 2 | single protein format | Scientific Literature |
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