# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3772718 | Functional | Agonist activity at human TAAR1 receptor expressed in HEK293T cells cotransfected with beta-2 receptor assessed as cAMP production at 100 uM by BRET assay | Homo sapiens | 9 | ALA3769363 | cell-based format | Scientific Literature | |
2. | ALA3772719 | Functional | Antagonist activity at human TAAR1 receptor expressed in HEK293T cells cotransfected with beta-2 receptor assessed as inhibition of beta-PEA-induced cAMP production at 100 uM by BRET assay | Homo sapiens | 8 | ALA3769363 | cell-based format | Scientific Literature | |
3. | ALA3772720 | Functional | Agonist activity at human TAAR1 receptor expressed in HEK293T cells cotransfected with beta-2 receptor assessed as cAMP production by BRET assay | Homo sapiens | 14 | ALA3769363 | cell-based format | Scientific Literature | |
4. | ALA3772721 | Functional | Agonist activity at human TAAR1 receptor expressed in HEK293T cells cotransfected with beta-2 receptor assessed as cAMP production by BRET assay relative to beta-PEA | Homo sapiens | 13 | ALA3769363 | cell-based format | Scientific Literature | |
5. | ALA3783756 | Functional | Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer | Homo sapiens | 38 | ALA3779872 | cell-based format | Scientific Literature | |
6. | ALA3783757 | Functional | Agonist activity at human TAAR1 expressed in recombinant HEK293 cells assessed as cAMP accumulation after 30 mins by luminometer relative to phenethylamine | Homo sapiens | 37 | ALA3779872 | cell-based format | Scientific Literature | |
7. | ALA3788458 | Functional | Agonist activity at human TAAR1 expressed in HEK293 cells assessed as increase in cAMP release after 30 mins by BRET assay | Homo sapiens | 1 | ALA3784953 | cell-based format | Scientific Literature | |
8. | ALA1930561 | Functional | Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assay | Homo sapiens | 19 | ALA1926662 | cell-based format | Scientific Literature | |
9. | ALA1930651 | Functional | Activation of human TAAR1 expressed in CHOK1 cells co-expressing Gq protein, Galpha16 using calcium4 dye by microplate reader | Homo sapiens | 1 | ALA1926662 | cell-based format | Scientific Literature | |
10. | ALA1930658 | Functional | Activation of human TAAR1 expressed in Syrian hamster AV12-664 cells co-expressing GalphaS protein assessed as accumulation of cAMP after 30 mins using cAMP XS EA/CL as substrate by luminescence method in presence of RX821002 and alprenolol | Homo sapiens | 4 | ALA1926662 | cell-based format | Scientific Literature | |
11. | ALA1930659 | Functional | Activation of human TAAR1 expressed in human HEK293T cells assessed as cAMP accumulation after 10 mins by BRET assay | Homo sapiens | 4 | ALA1926662 | cell-based format | Scientific Literature | |
12. | ALA1670082 | Binding | Inhibition of human TAAR1 | Homo sapiens | 3 | ALA1667822 | single protein format | Scientific Literature | |
13. | ALA1670128 | Functional | Antagonist activity at human TAAR1 assessed as reversal of endogenous beta-PEA effect | Homo sapiens | 3 | ALA1667822 | assay format | Scientific Literature | |
14. | ALA1670255 | Functional | Antagonist activity at humanTAAR1 assessed as residual stimulation by in vitro cAMP functional assay relative to control | Homo sapiens | 1 | ALA1667822 | assay format | Scientific Literature | |
15. | ALA1048859 | Functional | Activation of human TAAR1 expressed in CHOK1 cells assessed as cAMP accumulation at 0.1 to 1 uM | Homo sapiens | 9 | ALA1156046 | cell-based format | Scientific Literature | |
16. | ALA1048860 | Functional | Activation of human TAAR1 expressed in CHOK1 cells coexpressing Galpha16 assessed as calcium accumulation at 0.1 to 1 uM relative to beta-phenethylamine | Homo sapiens | 8 | ALA1156046 | cell-based format | Scientific Literature | |
17. | ALA1048862 | Functional | Activation of human TAAR1 expressed in CHOK1 cells assessed as cAMP accumulation at 10 uM relative to beta-phenethylamine | Homo sapiens | 3 | ALA1156046 | cell-based format | Scientific Literature | |
18. | ALA1048863 | Functional | Activation of human TAAR1 expressed in CHOK1 cells coexpressing Galpha16 assessed as calcium accumulation at 10 uM relative to beta-phenethylamine | Homo sapiens | 8 | ALA1156046 | cell-based format | Scientific Literature | |
19. | ALA1048864 | Functional | Activation of human TAAR1 expressed in CHOK1 cells coexpressing Galpha16 assessed as calcium accumulation | Homo sapiens | 1 | ALA1156046 | cell-based format | Scientific Literature | |
20. | ALA1048866 | Functional | Activation of human TAAR1 expressed in CHOK1 cells coexpressing Galpha16 assessed as calcium accumulation relative to control | Homo sapiens | 1 | ALA1156046 | cell-based format | Scientific Literature |