# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA976253 | Binding | Inhibition of human AIR carboxylase: SAICAR synthetase at 200 uM by coupled assay | Homo sapiens | 3 | ALA1139237 | single protein format | Scientific Literature | |
2. | ALA4418466 | Binding | Inhibition of wild type full length human PAICS using CAIR as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by ADP2 tracer-based fluorescence assay | Homo sapiens | 63 | ALA4418316 | single protein format | Patent Bioactivity Data | |
3. | ALA3991811 | Binding | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 243 | ALA3991601 | subcellular format | Kuster lab chemical proteomics drug profiling | |
4. | ALA4119030 | Binding | Binding affinity to PAICS in human NCI-H358 cells at 1 uM by mass spectrometry based pull down assay | Homo sapiens | 1 | ALA4118021 | cell-based format | Scientific Literature |