| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2090463 | A | Hydrolytic stability of the compound assessed as human NPP1-mediated hydrolysis measuring UMP formation after 2 hrs by HPLC analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA2090469 | A | Hydrolytic stability of the compound assessed as human NPP1-mediated hydrolysis measuring 5-OMe-UMP formation after 2 hrs by HPLC analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2090470 | A | Hydrolytic stability of the compound assessed as human NPP1-mediated hydrolysis after 2 hrs by HPLC analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA1805827 | B | Activity of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using Ap5A as the substrate at 100 uM after 30 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA1806207 | B | Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate at 100 uM after 15 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA1806210 | B | Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using Ap5A as the substrate at 100 uM after 30 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA1806211 | B | Inhibition of human NPP1 expressed in COS7 cells assessed as amount of inorganic phosphate released using ATP as the substrate at 100 uM after 15 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA1806215 | B | Inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA1806216 | B | Inhibition of human NPP1 expressed in COS7 cells assessed as enzyme-substrate-inhibitor dissociation constant using pnp-TMP as the substrate after 15 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA1806217 | B | Inhibition of human NPP1 in human HT29 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA1806218 | B | Inhibition of human NPP1 in human Saos2 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate after 15 mins by malachite green reagent method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA1004221 | B | Activity of human NPP1 expressed in human 293T cells assessed as drug hydrolysis at 100 uM after 20 mins by reverse-phase HPLC relative to p-nitrophenyl-thymidine-5-monophosphate | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA1005037 | B | Inhibition of human NPP1 expressed in human 293T cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA1054564 | B | Inhibition of NPP1 | 1 | single protein format | Scientific Literature | |||
| 15. | ALA1068584 | B | Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometry | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 16. | ALA1068585 | B | Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysis | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 17. | ALA1787511 | B | Inhibition of PC1 by in vitro Kinase-Glo assay | 13 | single protein format | Scientific Literature | |||
| 18. | ALA2182177 | A | Stability of the compound assessed as human eNPP1-mediated degradation of compound measuring increase in NMP level at pH 8.5 at 0.2 mM after 20 mins by HPLC relative to control | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 19. | ALA2390592 | A | Drug metabolism assessed as human nucleotide pyrophosphatase/phosphodiesterase1-mediated compound hydrolysis at 4.24 mM after 1 hr by HPLC analysis relative to ADP | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 20. | ALA3089316 | B | Competitive inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated at 25 to 100 uM for 3 mins before substrate addition measured after 15 mins by Dixon/Cornish Bowden method | Homo sapiens | 7 | cell-based format | Scientific Literature |
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