# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1023015 | B | Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry | Trypanosoma cruzi | 17 | ALA1152802 | assay format | Scientific Literature | |
2. | ALA1785240 | B | Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli using GAPDH and D-glyceraldehyde-3-phosphate | Trypanosoma cruzi | 22 | ALA1781931 | assay format | Scientific Literature | |
3. | ALA1785241 | B | Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli using GAPDH and D-glyceraldehyde-3-phosphate in presence of 0.01% Triton X-100 | Trypanosoma cruzi | 2 | ALA1781931 | assay format | Scientific Literature | |
4. | ALA1785088 | B | Non-competitive inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli assessed as dissociation constant for binary enzyme-inhibitor complex using NAD+ substrate by Lineweaver-Burk plot method | Trypanosoma cruzi | 2 | ALA1781931 | assay format | Scientific Literature | |
5. | ALA1785089 | B | Non-competitive inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli assessed as dissociation constant for ternary enzyme-substrate-inhibitor complex using NAD+ substrate by Lineweaver-Burk plot method | Trypanosoma cruzi | 2 | ALA1781931 | assay format | Scientific Literature | |
6. | ALA1785090 | B | Non-competitive inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli assessed as dissociation constant for binary enzyme-inhibitor complex using D-glyceraldehyde-3-phosphate substrate by Lineweaver-Burk plot method | Trypanosoma cruzi | 2 | ALA1781931 | assay format | Scientific Literature | |
7. | ALA1785091 | B | Non-competitive inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli assessed as dissociation constant for ternary enzyme-substrate-inhibitor complex using D-glyceraldehyde-3-phosphate substrate by Lineweaver-Burk plot method | Trypanosoma cruzi | 2 | ALA1781931 | assay format | Scientific Literature | |
8. | ALA2410458 | B | Inhibition of Trypanosoma cruzi glycosomal GAPDH | Trypanosoma cruzi | 1 | ALA2407047 | single protein format | Scientific Literature | |
9. | ALA2412696 | B | Non-competitive inhibition of Trypanosoma cruzi glycosomal GAPDH active site by ITC method | Trypanosoma cruzi | 3 | ALA2407047 | single protein format | Scientific Literature | |
10. | ALA2412697 | B | Competitive inhibition of Trypanosoma cruzi glycosomal GAPDH assessed as NAD+ Vmax by ITC method (Rvb = 0.24 +/- 0.01 uM/sec) | Trypanosoma cruzi | 7 | ALA2407047 | single protein format | Scientific Literature | |
11. | ALA2412698 | B | Competitive inhibition of Trypanosoma cruzi glycosomal GAPDH assessed as increase in NAD+ Km by ITC method (Rvb = 40.14 +/- 3.13 uM) | Trypanosoma cruzi | 7 | ALA2407047 | single protein format | Scientific Literature | |
12. | ALA2412700 | B | Competitive inhibition of Trypanosoma cruzi glycosomal GAPDH NAD+ binding site by ITC method | Trypanosoma cruzi | 7 | ALA2407047 | single protein format | Scientific Literature | |
13. | ALA3587616 | B | Inhibition of Trypanosoma cruzi gGAPDH | Trypanosoma cruzi | 1 | ALA3585239 | single protein format | Scientific Literature |