# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA899535 | F | Agonist activity at PAR2 expressed in human HT29 cells assessed as intracellular calcium release | Homo sapiens | 53 | ALA1137449 | cell-based format | Scientific Literature | |
2. | ALA899536 | F | Agonist activity at PAR2 expressed in 2-furoyl-LIGRLI-NH2 treated human HT29 cells assessed as intracellular calcium response | Homo sapiens | 1 | ALA1137449 | cell-based format | Scientific Literature | |
3. | ALA996091 | F | Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on intracellular calcium mobilization by R-SAT assay | Homo sapiens | 12 | ALA1140059 | cell-based format | Scientific Literature | |
4. | ALA996092 | F | Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on intracellular calcium mobilization by R-SAT assay relative to SLIGRL-NH2 | Homo sapiens | 12 | ALA1140059 | cell-based format | Scientific Literature | |
5. | ALA996093 | F | Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on phosphatidyl inositol hydrolysis | Homo sapiens | 2 | ALA1140059 | cell-based format | Scientific Literature | |
6. | ALA1001577 | F | Antagonist activity at human recombinant PAR2 expressed in A549 cells assessed as inhibition of SLIGKV-NH2-induced intracellular calcium mobilization | Homo sapiens | 2 | ALA1136992 | cell-based format | Scientific Literature | |
7. | ALA1001578 | F | Antagonist activity at human recombinant PAR2 expressed in A549 cells assessed as inhibition of SLIGKV-NH2-induced intracellular calcium mobilization at up to 10 uM | Homo sapiens | 2 | ALA1136992 | cell-based format | Scientific Literature | |
8. | ALA965447 | B | Binding affinity to PAR2 | 1 | ALA1150318 | single protein format | Scientific Literature | ||
9. | ALA1061658 | F | Antagonist activity at PAR2 expressed in Cos7 cells assessed as SLIGRl-mediated SRE-luciferase activity | 2 | ALA1153543 | cell-based format | Scientific Literature | ||
10. | ALA1262315 | B | Inhibition of PAR2-mediated IL1-beta and SLIGKV-NH2-induced interleukin-8 production in normal human epidermal keratinocytes at 10 uM by ELISA | Homo sapiens | 3 | ALA1255296 | assay format | Scientific Literature | |
11. | ALA1262316 | B | Inhibition of PAR2-mediated SLIGKV-NH2-induced interleukin-8 production in normal human epidermal keratinocytes at 10 uM preincubated for 24 hrs by ELISA | Homo sapiens | 2 | ALA1255296 | assay format | Scientific Literature | |
12. | ALA1262317 | B | Inhibition of PAR2-mediated SLIGKV-NH2-induced interleukin-8 production in normal human epidermal keratinocytes at 100 uM preincubated for 24 hrs by ELISA | Homo sapiens | 2 | ALA1255296 | assay format | Scientific Literature | |
13. | ALA1262318 | B | Inhibition of PAR2-mediated SLIGKV-NH2-induced interleukin-8 production in normal human epidermal keratinocytes at 5 uM preincubated for 24 hrs by ELISA | Homo sapiens | 1 | ALA1255296 | assay format | Scientific Literature | |
14. | ALA1262319 | B | Inhibition of PAR2-mediated SLIGKV-NH2-induced interleukin-8 production in normal human epidermal keratinocytes up to 100 uM preincubated for 24 hrs by ELISA | Homo sapiens | 1 | ALA1255296 | assay format | Scientific Literature | |
15. | ALA1262320 | B | Inhibition of PAR2-mediated SLIGKV-NH2-induced interleukin-8 production in normal human epidermal keratinocytes preincubated for 24 hrs by ELISA | Homo sapiens | 3 | ALA1255296 | assay format | Scientific Literature | |
16. | ALA1274353 | F | Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium release at 50 uM relative to 2f-LIGELI-NH2 | Homo sapiens | 10 | ALA1268911 | cell-based format | Scientific Literature | |
17. | ALA1274355 | F | Agonist activity at human PAR2 receptor in HEK293 cells assessed as induction of intracellular calcium release | Homo sapiens | 4 | ALA1268911 | cell-based format | Scientific Literature | |
18. | ALA1274356 | F | Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium release | Homo sapiens | 11 | ALA1268911 | cell-based format | Scientific Literature | |
19. | ALA1274357 | F | Antagonist activity at PAR2 receptor in human HT-29 cells assessed as inhibition of intracellular calcium release | Homo sapiens | 2 | ALA1268911 | cell-based format | Scientific Literature | |
20. | ALA1274358 | F | Antagonist activity at PAR2 receptor in human HT-29 cells assessed as inhibition of intracellular calcium release at 5 uM relative to SLIGRLI-NH2 | Homo sapiens | 6 | ALA1268911 | cell-based format | Scientific Literature |