| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA955648 | F | Activity at LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced intracellular calcium concentration | 12 | ALA1150359 | cell-based format | Scientific Literature | ||
| 2. | ALA1073936 | F | Antagonist activity at LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced intracellular calcium response | 8 | ALA1152645 | cell-based format | Scientific Literature | ||
| 3. | ALA2344987 | B | Intrinsic activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 relative to LPA | Homo sapiens | 11 | ALA2331094 | cell-based format | Scientific Literature | |
| 4. | ALA2344995 | B | Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 | Homo sapiens | 11 | ALA2331094 | cell-based format | Scientific Literature | |
| 5. | ALA3624268 | F | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced calcium mobilization by Fura-2 AM probe-based fluorometric analysis | Homo sapiens | 1 | ALA3621155 | cell-based format | Scientific Literature | |
| 6. | ALA3624409 | F | Antagonist activity at human LPA4 receptor expressed in rat B103 cells assessed as inhibition of LPA-induced calcium mobilization preincubated for 30 mins followed by LPA induction by FLIPR Calcium 4 dye-based fluorometric analysis | Homo sapiens | 1 | ALA3621155 | cell-based format | Scientific Literature | |
| 7. | ALA3626961 | F | Antagonist activity at human LPA4 receptor expressed in CHO cells assessed as inhibition of LPA-induced Ca2+ mobilization by FURA-2AM dye based fluorescence assay | Homo sapiens | 2 | ALA3621086 | cell-based format | Scientific Literature | |
| 8. | ALA3998927 | F | Agonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular calcium level up to 10 uM measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assay | Homo sapiens | 3 | ALA3997796 | cell-based format | Scientific Literature | |
| 9. | ALA3998933 | F | Antagonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as inhibition of LPA-induced intracellular calcium level up to 100 uM measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assay | Homo sapiens | 5 | ALA3997796 | cell-based format | Scientific Literature | |
| 10. | ALA3998950 | F | Agonist activity at LPA4 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular calcium level measured every 3.42 secs for 70 secs by Fura-2-AM dye based fluorescence assay | Homo sapiens | 1 | ALA3997796 | cell-based format | Scientific Literature | |
| 11. | ALA4432714 | F | Agonist activity at LPA receptor 4 (unknown origin) assessed as calcium mobilization after 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA4431364 | single protein format | Scientific Literature | |
| 12. | ALA4432725 | F | Antagonist activity at LPA receptor 4 (unknown origin) assessed as inhibition of LPA induced calcium mobilization at 0.01 to 10 uM after 30 mins by fluorescence analysis | Homo sapiens | 1 | ALA4431364 | single protein format | Scientific Literature | |
| 13. | ALA4610708 | F | Agonist activity at human LPA4 expressed in rat B103 cells assessed as increase in intracellular calcium level by Fluo-4 NW dye based fluorescence assay | Homo sapiens | 1 | ALA4610001 | cell-based format | Scientific Literature | |
| 14. | ALA4883514 | B | PRESTO-Tango GPCRome screening (LPA4) | 1 | ALA4507309 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 15. | ALA5052896 | B | Activation of human GPR23 stably expressed in CHO cells expressing Galpha16 | Homo sapiens | 1 | ALA5052820 | cell-based format | Patent Bioactivity Data |
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