| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1826922 | B | Activity of PIP5K1A kinase at 1 uM | 1 | single protein format | Scientific Literature | |||
| 2. | ALA1908521 | B | Binding constant for PIP5K1A kinase domain | 72 | single protein format | Scientific Literature | |||
| 3. | ALA981742 | B | Inhibition of PIP5K1A at 3 uM | 1 | single protein format | Scientific Literature | |||
| 4. | ALA1017904 | B | Inhibition of PIP5K1A assessed as enzyme activity relative to control | 3 | single protein format | Scientific Literature | |||
| 5. | ALA1061923 | B | Binding constant for full-length PIP5K1A | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 6. | ALA1057594 | B | Inhibition of PIP5K1A assessed as enzyme activity at 1 uM relative to untreated control | 1 | single protein format | Scientific Literature | |||
| 7. | ALA1166810 | B | Inhibition of PIP5K1A at 1 uM | 10 | single protein format | Scientific Literature | |||
| 8. | ALA1175216 | B | Inhibition of PIP5K1A at 10 uM | 2 | single protein format | Scientific Literature | |||
| 9. | ALA1244925 | B | Binding affinity to PIP5K1A | 7 | single protein format | Scientific Literature | |||
| 10. | ALA2212497 | B | Inhibition of PIP5K1A assessed as residual activity at 10 uM relative to control | 1 | single protein format | Scientific Literature | |||
| 11. | ALA2394176 | B | Competitive binding affinity to PIP5K1A (unknown origin) assessed as enzyme remaining bound to anchored active-site ligand at 10 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 12. | ALA2429135 | B | Competitive binding affinity to PIP5K1A (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA3111945 | B | Inhibition of PIP5K1A (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA3130695 | B | Inhibition of human PIP5K1alpha assessed as residual activity at 1 uM relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA4025324 | B | Inhibition of wild-type human full length PIP5K1A (M1 to H562 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA4044135 | B | Inhibition of wild-type human full length PIP5K1A (M1 to H562 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4054902 | B | Inhibition of human PIP5K1A (M1 to H562 residues) expressed in bacterial expression system assessed as residual activity at 50 nM by KINOMEscan assay relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 18. | ALA4157214 | B | Binding affinity to wild-type human full length PIP5K1A (M1 to H562 residues) expressed in bacterial expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4181238 | B | Inhibition of recombinant human full length N-terminal His6-tagged PIP5K1alpha expressed in baculovirus Sf21 insect cells at 10 uM by filter binding radioactive ATP transferase assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4185993 | B | Binding affinity to wild-type human full length PIP5K1A (M1 to H562 residues) expressed in Escherichia coli BL21 at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | assay format | Scientific Literature |
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