# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA995016 | B | Inhibition of RIOK1 at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
2. | ALA1017914 | B | Inhibition of RIOK1 assessed as enzyme activity relative to control | 2 | ALA1151738 | single protein format | Scientific Literature | ||
3. | ALA1051258 | B | Binding constant for full-length RIOK1 | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
4. | ALA1052944 | B | Inhibition of RIOK1 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
5. | ALA1166840 | B | Inhibition of RIOK1 at 1 uM | 10 | ALA1165965 | single protein format | Scientific Literature | ||
6. | ALA1175250 | B | Inhibition of RIOK1 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
7. | ALA1244955 | B | Binding affinity to RIOK1 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
8. | ALA1685867 | B | Inhibition of ROCK1 at 0.1 uM | 4 | ALA1681705 | single protein format | Scientific Literature | ||
9. | ALA1686083 | B | Inhibition of ROCK1 at 1 uM | 4 | ALA1681705 | single protein format | Scientific Literature | ||
10. | ALA1826192 | B | Activity of RIOK1 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
11. | ALA1838168 | B | Inhibition of ROCK1 at 1 uM | 2 | ALA1833910 | single protein format | Scientific Literature | ||
12. | ALA1908838 | B | Binding constant for RIOK1 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
13. | ALA2212012 | B | Inhibition of RIOK1 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
14. | ALA2396459 | B | Competitive binding affinity to RIOK1 (unknown origin) assessed as enzyme remaining bound to anchored active-site ligand at 10 uM relative to control | Homo sapiens | 1 | ALA2390846 | single protein format | Scientific Literature | |
15. | ALA2429004 | B | Competitive binding affinity to RIOK1 (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 3 | ALA2424622 | single protein format | Scientific Literature | |
16. | ALA4025358 | B | Inhibition of wild-type human full length RIOK1 (M1 to K568 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
17. | ALA4044169 | B | Inhibition of wild-type human full length RIOK1 (M1 to K568 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | assay format | Scientific Literature | |
18. | ALA4054905 | B | Inhibition of full length human RIOK1 (M1 to K568 residues) expressed in bacterial expression system assessed as residual activity at 50 nM by KINOMEscan assay relative to control | Homo sapiens | 2 | ALA4052645 | assay format | Scientific Literature | |
19. | ALA4157248 | B | Binding affinity to wild-type human full length RIOK1 (M1 to K568 residues) expressed in bacterial expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
20. | ALA4186027 | B | Binding affinity to wild-type human full length RIOK1 (M1 to K568 residues) expressed in Escherichia coli BL21 at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | assay format | Scientific Literature |