# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3583864 | Binding | Inhibition of human LDH-A by biochemical assay | Homo sapiens | 34 | ALA3580578 | single protein format | Scientific Literature | |
2. | ALA3611226 | Binding | Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as NADH oxidation for 3 mins by fluorimetric method | Homo sapiens | 14 | ALA3608299 | assay format | Scientific Literature | |
3. | ALA3611227 | Binding | Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level after 3 hrs | Homo sapiens | 14 | ALA3608299 | cell-based format | Scientific Literature | |
4. | ALA3611229 | Binding | Inhibition of human liver purified lactate dehydrogenase-A using pyruvate as substrate assessed as disappearance of NADH fluorescence | Homo sapiens | 1 | ALA3608299 | assay format | Scientific Literature | |
5. | ALA3611230 | Binding | Inhibition of human liver purified lactate dehydrogenase-A using NADH as substrate assessed as disappearance of NADH fluorescence | Homo sapiens | 1 | ALA3608299 | assay format | Scientific Literature | |
6. | ALA3611231 | Binding | Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of intracellular lactate level at 40 uM after 3 hrs | Homo sapiens | 1 | ALA3608299 | cell-based format | Scientific Literature | |
7. | ALA3611235 | Binding | Inhibition of lactate dehydrogenase-A in human Raji cells assessed as reduction of NAD+ regeneration at 40 uM | Homo sapiens | 1 | ALA3608299 | cell-based format | Scientific Literature | |
8. | ALA3611243 | Binding | Inhibition of lactate dehydrogenase-A in human Raji cells assessed as NAD level per 10'6 cells at 40 uM after 18 hrs (Rvb = 365 pmol) | Homo sapiens | 1 | ALA3608299 | cell-based format | Scientific Literature | |
9. | ALA3611244 | Binding | Inhibition of lactate dehydrogenase-A in human Raji cells assessed as NADH level per 10'6 cells at 40 uM after 18 hrs (Rvb = 24 pmol) | Homo sapiens | 1 | ALA3608299 | cell-based format | Scientific Literature | |
10. | ALA3750716 | Binding | Inhibition of human LDHA using pyruvate as substrate assessed as disappearance of NADH preincubated for 10 mins followed by substrate addition every 2.5 secs for 10 mins by fluorescence analysis | Homo sapiens | 5 | ALA3745616 | single protein format | Scientific Literature | |
11. | ALA3750424 | Binding | Inhibition of human LDHA using pyruvate as substrate assessed as disappearance of NADH | Homo sapiens | 2 | ALA3745616 | single protein format | Scientific Literature | |
12. | ALA3768543 | Binding | Competitive inhibition of human LDH5 meaured for 3 mins in presence of pyruvate by fluorescence analysis | Homo sapiens | 1 | ALA3763153 | single protein format | Scientific Literature | |
13. | ALA3768756 | Binding | Competitive inhibition of human LDH5 in presence of NADH | Homo sapiens | 26 | ALA3763153 | single protein format | Scientific Literature | |
14. | ALA3768758 | Binding | Competitive inhibition of human LDH5 meaured for 3 mins in presence of NADH by fluorescence analysis | Homo sapiens | 1 | ALA3763153 | single protein format | Scientific Literature | |
15. | ALA3768762 | Binding | Competitive inhibition of human LDH5 incubated for 15 mins in presence of NADH by fluorescence analysis | Homo sapiens | 2 | ALA3763153 | single protein format | Scientific Literature | |
16. | ALA3768763 | Binding | Potency index, ratio of IC50 for sodium oxamate to IC50 for test compound for inhibition of human LDH5 in presence of NADH | Homo sapiens | 1 | ALA3763153 | single protein format | Scientific Literature | |
17. | ALA706376 | Binding | inhibitory activity against Plasmodium falciparum LDH (pLDH) | Plasmodium falciparum | 10 | ALA1131124 | single protein format | Scientific Literature | |
18. | ALA709293 | Binding | Apparent inhibition constant against mammalian lactate dehydrogenase (LDH) | Sus scrofa | 1 | ALA1127319 | single protein format | Scientific Literature | |
19. | ALA859428 | Binding | Michaelis-Menten constant against mammalian lactate dehydrogenase (LDH) | Sus scrofa | 1 | ALA1127319 | single protein format | Scientific Literature | |
20. | ALA4350241 | Binding | Inhibition of recombinant human LDHA expressed in Escherichia coli using lactate as substrate incubated for 30 mins followed by substrate addition | Homo sapiens | 4 | ALA4346746 | assay format | Scientific Literature |