# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2091983 | B | Activation of human TRPA1 assessed as stimulation of intracellular Ca2+ levels | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA1820158 | F | Agonist activity at human TRPA1 channel expressed in HEK293 cells assessed as calcium influx measured at every 1 second for 60 seconds by fluorescence analysis | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
3. | ALA2071975 | F | Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Zn2+-induced intracellular calcium flux by FLIPR assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
4. | ALA2071976 | F | Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Ca2+-induced intracellular calcium flux by FLIPR assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
5. | ALA2071977 | F | Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Ca2+-induced channel current by whole cell patch clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA2071978 | F | Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Ca2+-induced channel current measured after compound washout by whole cell patch clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA1944172 | F | Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of 5H-dibenzo[b,e]azepine-10-carboxylic acid methyl ester-induced increase in intracellular calcium by Fluo4-AM based fluorometric assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
8. | ALA1944174 | F | Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of N-methyl-maleimide-induced current by patch clamp assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA1944277 | B | Binding affinity for TRPA1 in presence of benzylmercaptane | 1 | single protein format | Scientific Literature | |||
10. | ALA1949457 | F | Antagonist activity at human TRPA1 expressed in human IMR90 cells assessed as inhibition of acrolein-induced calcium influx after 40 mins by fluorescence analysis | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
11. | ALA1949458 | F | Antagonist activity at human TRPA1 expressed in human IMR90 cells assessed as inhibition of acrolein-induced calcium influx at 30 uM after 40 mins by fluorescence analysis | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
12. | ALA1949463 | F | Antagonist activity at human TRPA1 expressed in CHO cells assessed as inhibition of calcium influx | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA1949464 | F | Antagonist activity at human TRPA1 expressed in human IMR90 cells assessed as inhibition of acrolein-induced calcium influx at 3 uM after 40 mins by fluorescence analysis | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
14. | ALA1949465 | F | Antagonist activity at human TRPA1 expressed in human IMR90 cells assessed as inhibition of acrolein-induced calcium influx at 1 uM after 40 mins by fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA940160 | B | Activation of TRPA1 | 13 | single protein format | Scientific Literature | |||
16. | ALA966836 | F | Agonist activity at human TRPA1 channel expressed in xenopus oocytes assessed as membrane currents by two electrode voltage-clamp technique | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA966837 | B | Reversal of activation of human TRPA1 channel expressed in xenopus oocytes by two electrode voltage-clamp technique in presence of ruthenium red | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA1049519 | F | Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate count | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
19. | ALA1049520 | F | Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate count | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
20. | ALA1049521 | F | Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate count relative to cinnamaldehyde | Homo sapiens | 19 | cell-based format | Scientific Literature |