# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2073527 | B | Inhibition of IKKbeta in mouse CIA model splenocytes assessed as inhibition of TNFalpha production after 72 hrs by ELISA | Mus musculus | 14 | cell-based format | Scientific Literature | ||
2. | ALA1001305 | B | Induction of IKK-beta-mediated IkappaBalpha degradation in IFN-stimulated mouse L929sA cells at 2.8 ug/ml by Western blot | Mus musculus | 3 | cell-based format | Scientific Literature | ||
3. | ALA1001306 | B | Induction of IKK-beta-hyperphosphorylation in IFN-stimulated mouse L929sA cells at 2.8 ug/ml by Western blot | Mus musculus | 3 | cell-based format | Scientific Literature | ||
4. | ALA1002118 | B | Reversal of induction of IKK-beta-hyperphosphorylation in IFN-stimulated mouse L929sA cells at 2.8 ug/ml in presence of 5 mM dithiothreitol | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA1105833 | B | Inhibition of LPS-stimulated IkappaB degradation in mouse RAW264.7 cells assessed as cellular IkappaB level at 5 uM treated after LPS-stimulation for 24 hrs measured after 60 mins by Western blotting | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA2209719 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced MCP1 phosphorylation at 25 uM by Northern blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA2209720 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced IkappaBalpha phosphorylation at 25 uM by Northern blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
8. | ALA2209721 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced MCP1 phosphorylation at 25 uM by Northern blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
9. | ALA2209722 | B | Inhibition of IKKebta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced IkappaBalpha phosphorylation at 25 uM by Northern blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
10. | ALA2209723 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced RelA phosphorylation at 25 uM after 5 mins by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
11. | ALA2209724 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced phosphorylation at 25 uM after 5 mins by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
12. | ALA2209725 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced IkappaBalpha phosphorylation at 25 uM after 5 mins by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
13. | ALA2209726 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced RelA phosphorylation at 25 uM after 5 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
14. | ALA2209727 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced phosphorylation at 25 uM after 5 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
15. | ALA2209728 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced IkappaBalpha phosphorylation at 25 uM after 5 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
16. | ALA2209729 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced IkappaBalpha degradation at 50 uM up to 90 mins by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
17. | ALA2212028 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced IkappaBalpha phosphorylation at 50 uM up to 90 mins by Western blot analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
18. | ALA2212030 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced IkappaBalpha degradation at 50 uM up to 90 mins by Western blot analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
19. | ALA2212031 | B | Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced IkappaBalpha phosphorylation at 50 uM up to 90 mins by Western blot analysis | Mus musculus | 5 | cell-based format | Scientific Literature | ||
20. | ALA3367073 | B | Inhibition of LPS/IFNgamma-induced IKKbeta phosphorylation in mouse BV2 cells at 1 to 4 uM pre-incubated for 30 mins before LPS/IFNgamma challenge for 1 hr by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature |