# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2015861 | B | Inhibition of glucosylceramide synthase in mouse RAW cells up to 20 uM preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence scanner | Mus musculus | 48 | cell-based format | Scientific Literature | ||
2. | ALA2015862 | B | Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluorescence scanner | Mus musculus | 53 | cell-based format | Scientific Literature | ||
3. | ALA970437 | B | Inhibition mouse glucosylceramide synthase | Mus musculus | 2 | single protein format | Scientific Literature | ||
4. | ALA1656917 | B | Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assay | Mus musculus | 26 | cell-based format | Scientific Literature | ||
5. | ALA2168222 | B | Inhibition of GCS activity in mouse tissue homogenate at 250 uM | Mus musculus | 3 | assay format | Scientific Literature | ||
6. | ALA2168423 | B | Inhibition of GCS activity in mouse tissue homogenate at 50 uM | Mus musculus | 3 | assay format | Scientific Literature | ||
7. | ALA5049081 | B | Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hr by RapidFire mass spectrometry | Mus musculus | 2 | single protein format | Scientific Literature | ||
8. | ALA5152881 | B | Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysis | Mus musculus | 3 | single protein format | Scientific Literature | ||
9. | ALA5225977 | B | Inhibition of GCS in mouse fibroblast | Mus musculus | 2 | cell-based format | Scientific Literature | ||
10. | ALA5226005 | F | Invivo inhibition of GCS in C57 mouse assessed as reduction in brain GlcCer d18:1/18:0 concentration at 30 to 100 mg/kg, po measured after 8 hrs by LC-MS/MS method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA5226006 | F | Invivo inhibition of GCS in C57 mouse assessed as reduction in brain GlcCer d18:1/18:0 concentration measured after 8 hrs by LC-MS/MS method | Mus musculus | 1 | assay format | Scientific Literature | ||
12. | ALA5263630 | B | Inhibition of GSG in mouse MEB5 cells | Mus musculus | 2 | cell-based format | Scientific Literature | ||
13. | ALA5304915 | F | Mouse GCS enzymatic assay | Mus musculus | 2 | assay format | Donated Chemical Probes - SGC Frankfurt |