# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA972086 | B | Inhibition of platelet derived growth factor-induced endogenous association of Cdc42 with GST-PAK-RBD in human U87MG cells after 5 mins by Western blot analysis | Homo sapiens | 1 | ALA1156526 | cell-based format | Scientific Literature | |
2. | ALA970412 | B | Inhibition of Cdc42-PAK-RBD complex formation in platelet derived growth factor-induced human U87MG cells at 50 uM by fluorescence anisotropy | Homo sapiens | 1 | ALA1156526 | cell-based format | Scientific Literature | |
3. | ALA970426 | B | Binding affinity at Cdc42 at 1 uM by fluorescence anisotropy | 1 | ALA1156526 | single protein format | Scientific Literature | ||
4. | ALA1035283 | B | Inhibition of Cdc42 | 4 | ALA1158458 | single protein format | Scientific Literature | ||
5. | ALA1035284 | B | Inhibition of PDGF-BB-stimulated Cdc42 activity in human aortic smooth muscle cells assessed as reduction in ratio of Cdc42GTP/Cdc42 levels at 25 uM after 4 hrs by pull-down assay | Homo sapiens | 5 | ALA1158458 | assay format | Scientific Literature | |
6. | ALA1053689 | B | Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP at 50 uM after 40 mins by nucleotide binding competition assay | 23 | ALA1155205 | single protein format | Scientific Literature | ||
7. | ALA1053691 | B | Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assay | 11 | ALA1155205 | single protein format | Scientific Literature | ||
8. | ALA1066161 | B | Inhibition of Cdc42 | 13 | ALA1157712 | single protein format | Scientific Literature | ||
9. | ALA1117932 | B | Inhibition of CDc42 | 8 | ALA1155525 | single protein format | Scientific Literature | ||
10. | ALA1120087 | B | Inhibition of CDC42 | 1 | ALA1155533 | single protein format | Scientific Literature | ||
11. | ALA1226170 | B | Inhibition of Cdc42 binding to PIP2 liposomes at 100 uM after 10 mins | 1 | ALA1221177 | microsome format | Scientific Literature | ||
12. | ALA1226173 | B | Inhibition of GEF-independent nucleotide exchange activity of prenylated Cdc42 after 3 mins in presence of 4 mM Mg2+ chelator EDTA | 2 | ALA1221177 | single protein format | Scientific Literature | ||
13. | ALA1226174 | B | Inhibition of GEF-independent nucleotide exchange activity of nonprenylated Cdc42 at 100 uM after 10 mins in presence of 4 mM EDTA | 1 | ALA1221177 | single protein format | Scientific Literature | ||
14. | ALA1226175 | B | Effect on Cdc42-mediated cellular response in human U373MG cells assessed as reorientation of golgi complex 15 uM after 6 hrs by epifluorescence assay | Homo sapiens | 1 | ALA1221177 | cell-based format | Scientific Literature | |
15. | ALA1226186 | B | Inhibition of nucleotide exchange activity of PIP2-stimulated Cdc42 at 25 uM by liquid scintillation counting | 3 | ALA1221177 | single protein format | Scientific Literature | ||
16. | ALA1226187 | B | Effect on GEF interaction with PIP2-stimulated Cdc42 at 25 uM by liquid scintillation counting | 3 | ALA1221177 | single protein format | Scientific Literature | ||
17. | ALA1226188 | B | Effect on nucleotide binding activity of PIP2-stimulated Cdc42 at 25 uM by liquid scintillation counting | 3 | ALA1221177 | single protein format | Scientific Literature | ||
18. | ALA1226189 | B | Inhibition of GEF-independent nucleotide exchange activity of prenylated Cdc42 assessed as protein dissociation from RhoGD11 complex at 100 uM after 3 mins in presence of 4 mM Mg2+ chelator EDTA | 2 | ALA1221177 | single protein format | Scientific Literature | ||
19. | ALA2210939 | B | Inhibition of recombinant CDC42 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATP | 1 | ALA2203238 | single protein format | Scientific Literature | ||
20. | ALA3816443 | B | Induction of degradation of halo-tagged human Cdc42 expressed in HEK293 cells at 1 uM after 6 hrs by Western blot analysis | Homo sapiens | 2 | ALA3813609 | cell-based format | Scientific Literature |