| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA996674 | F | Antagonist activity at mouse TLR9 expressed in HEK293 cells assessed as inhibition of 5'-CTATCTGTCGTTCTCTGT-3'-induced NF-kappaB activation by SEAP reporter gene assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA996675 | F | Agonist activity at mouse TLR9 expressed in HEK293 cells assessed as activation of NF-kappaB at 10 ug/mL by SEAP reporter gene assay | Mus musculus | 10 | cell-based format | Scientific Literature | ||
| 3. | ALA996676 | F | Antagonist activity at mouse TLR9 expressed in HEK293 cells assessed as inhibition of 5'-CTATCTGACGTTCTCTGT-3'-induced NF-kappaB activation by SEAP reporter gene assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA996677 | F | Agonist activity at TLR9 in mouse J774 cells assessed as of NF-kappaB activation | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA996678 | F | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3'-induced NF-kappaB activation pretreated for 1 hr | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA996679 | F | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of 5'-UGCUGUUCUG-X-GUCUUGUCGU-5'-induced NF-kappaB activation | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA996680 | F | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of LPS-induced NF-kappaB activation treated 1 hr before LPS induction | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA996682 | F | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3'-induced NF-kappaB activation | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA996683 | F | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3'-induced NF-kappaB activation pretreated for 30 mins | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA997570 | F | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3'-induced NF-kappaB activation pretreated for 1 hr in presence of increasing levels of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3' | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA997571 | F | Antagonist activity at mouse TLR9 expressed in HEK293 cells assessed as inhibition of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3'-induced NF-kappaB activation pretreated for 1 hr in presence of increasing levels of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3' | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA1053993 | B | Activation of mouse TLR9 expressed in HEK293 cells assessed as NF-kappaB level at 0.1 ug/mL after 18 hrs by reporter gene assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 13. | ALA1054781 | B | Activation of mouse TLR9 expressed in HEK293 cells assessed as NF-kappaB level at 0.3 ug/mL after 18 hrs by reporter gene assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 14. | ALA1054782 | B | Activation of mouse TLR9 expressed in HEK293 cells assessed as NF-kappaB level at 1 ug/mL after 18 hrs by reporter gene assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 15. | ALA1102311 | B | Activation of mouse TLR9 expressed in HEK293 assessed as induction of NF-kappaB activity reporter gene assay | Mus musculus | 32 | cell-based format | Scientific Literature | ||
| 16. | ALA1113891 | B | Activation of mouse TLR9 expressed in HEK293 cells assessed as induction of NF-kappaB activity after 18 hrs by SEAP assay | Mus musculus | 8 | cell-based format | Scientific Literature | ||
| 17. | ALA1113892 | B | Activation of mouse TLR9 expressed in HEK293 cells assessed as induction of NF-kappaB activity at 1 to 10 ug/ml after 18 hrs by SEAP assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA1113893 | B | Induction of TLR9-mediated IL12 production in C57BL/6 mouse spleen cells after 24 hrs by ELISA | Mus musculus | 9 | cell-based format | Scientific Literature | ||
| 19. | ALA1113894 | B | Induction of TLR9-mediated IL6 production in C57BL/6 mouse spleen cells after 24 hrs by ELISA | Mus musculus | 9 | cell-based format | Scientific Literature | ||
| 20. | ALA2209292 | B | Inhibition of MyD88 recruitment to TLR9 in C57BL/6 mouse BMDM cells assessed as inhibition of CpG-induced p38 MAPK activity up to 90 mins | Mus musculus | 1 | cell-based format | Scientific Literature |
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