# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1102311 | Binding | Activation of mouse TLR9 expressed in HEK293 assessed as induction of NF-kappaB activity reporter gene assay | Mus musculus | 32 | ALA1154352 | cell-based format | Scientific Literature | |
2. | ALA1113891 | Binding | Activation of mouse TLR9 expressed in HEK293 cells assessed as induction of NF-kappaB activity after 18 hrs by SEAP assay | Mus musculus | 8 | ALA1157912 | cell-based format | Scientific Literature | |
3. | ALA1113892 | Binding | Activation of mouse TLR9 expressed in HEK293 cells assessed as induction of NF-kappaB activity at 1 to 10 ug/ml after 18 hrs by SEAP assay | Mus musculus | 1 | ALA1157912 | cell-based format | Scientific Literature | |
4. | ALA1113893 | Binding | Induction of TLR9-mediated IL12 production in C57BL/6 mouse spleen cells after 24 hrs by ELISA | Mus musculus | 9 | ALA1157912 | cell-based format | Scientific Literature | |
5. | ALA1113894 | Binding | Induction of TLR9-mediated IL6 production in C57BL/6 mouse spleen cells after 24 hrs by ELISA | Mus musculus | 9 | ALA1157912 | cell-based format | Scientific Literature | |
6. | ALA4361581 | Binding | Antagonist activity at TLR9 in mouse RAW264.7 cells assessed as reduction in CpG ODN-induced TNFalpha secretion at 20 to 80 uM after 24 hrs by ELISA | Mus musculus | 1 | ALA4359843 | cell-based format | Scientific Literature | |
7. | ALA1053993 | Binding | Activation of mouse TLR9 expressed in HEK293 cells assessed as NF-kappaB level at 0.1 ug/mL after 18 hrs by reporter gene assay | Mus musculus | 7 | ALA1152452 | cell-based format | Scientific Literature | |
8. | ALA1054781 | Binding | Activation of mouse TLR9 expressed in HEK293 cells assessed as NF-kappaB level at 0.3 ug/mL after 18 hrs by reporter gene assay | Mus musculus | 7 | ALA1152452 | cell-based format | Scientific Literature | |
9. | ALA1054782 | Binding | Activation of mouse TLR9 expressed in HEK293 cells assessed as NF-kappaB level at 1 ug/mL after 18 hrs by reporter gene assay | Mus musculus | 7 | ALA1152452 | cell-based format | Scientific Literature | |
10. | ALA996674 | Functional | Antagonist activity at mouse TLR9 expressed in HEK293 cells assessed as inhibition of 5'-CTATCTGTCGTTCTCTGT-3'-induced NF-kappaB activation by SEAP reporter gene assay | Mus musculus | 2 | ALA1140884 | cell-based format | Scientific Literature | |
11. | ALA996675 | Functional | Agonist activity at mouse TLR9 expressed in HEK293 cells assessed as activation of NF-kappaB at 10 ug/mL by SEAP reporter gene assay | Mus musculus | 10 | ALA1140884 | cell-based format | Scientific Literature | |
12. | ALA996676 | Functional | Antagonist activity at mouse TLR9 expressed in HEK293 cells assessed as inhibition of 5'-CTATCTGACGTTCTCTGT-3'-induced NF-kappaB activation by SEAP reporter gene assay | Mus musculus | 3 | ALA1140884 | cell-based format | Scientific Literature | |
13. | ALA996677 | Functional | Agonist activity at TLR9 in mouse J774 cells assessed as of NF-kappaB activation | Mus musculus | 3 | ALA1140884 | cell-based format | Scientific Literature | |
14. | ALA996678 | Functional | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3'-induced NF-kappaB activation pretreated for 1 hr | Mus musculus | 2 | ALA1140884 | cell-based format | Scientific Literature | |
15. | ALA996679 | Functional | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of 5'-UGCUGUUCUG-X-GUCUUGUCGU-5'-induced NF-kappaB activation | Mus musculus | 1 | ALA1140884 | cell-based format | Scientific Literature | |
16. | ALA996680 | Functional | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of LPS-induced NF-kappaB activation treated 1 hr before LPS induction | Mus musculus | 1 | ALA1140884 | cell-based format | Scientific Literature | |
17. | ALA996682 | Functional | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3'-induced NF-kappaB activation | Mus musculus | 1 | ALA1140884 | cell-based format | Scientific Literature | |
18. | ALA996683 | Functional | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3'-induced NF-kappaB activation pretreated for 30 mins | Mus musculus | 1 | ALA1140884 | cell-based format | Scientific Literature | |
19. | ALA997570 | Functional | Antagonist activity at TLR9 in mouse J774 cells assessed as inhibition of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3'-induced NF-kappaB activation pretreated for 1 hr in presence of increasing levels of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3' | Mus musculus | 1 | ALA1140884 | cell-based format | Scientific Literature | |
20. | ALA997571 | Functional | Antagonist activity at mouse TLR9 expressed in HEK293 cells assessed as inhibition of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3'-induced NF-kappaB activation pretreated for 1 hr in presence of increasing levels of 5'-TCTGACRTTCT-X-TCTTRCAGTCT-3' | Mus musculus | 1 | ALA1140884 | cell-based format | Scientific Literature |