# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3631270 | Binding | Inhibition of LATS (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | single protein format | Scientific Literature | |
2. | ALA3748232 | Binding | Inhibition of human LATS1 using [KKRNRRLSVA] as substrate | Homo sapiens | 1 | ALA3745707 | single protein format | Scientific Literature | |
3. | ALA1166044 | Binding | Inhibition of LATS1 at 1 uM | 6 | ALA1165965 | single protein format | Scientific Literature | ||
4. | ALA1174813 | Binding | Inhibition of LATS1 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
5. | ALA1244478 | Binding | Binding affinity to LATS1 | 7 | ALA1240346 | single protein format | Scientific Literature | ||
6. | ALA1826200 | Binding | Activity of LATS1 kinase at 1 uM | 1 | ALA1821651 | single protein format | Scientific Literature | ||
7. | ALA4352418 | Binding | Inhibition of human LATS1 at 10 uM using KKRNRRLSVA as substrate in presence of [gamma-33P]-ATP | Homo sapiens | 1 | ALA4350963 | single protein format | Scientific Literature | |
8. | ALA4357951 | Binding | Binding affinity to wild-type human partial length LATS1 (Q678 to V1130 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4354843 | assay format | Scientific Literature | |
9. | ALA1908660 | Binding | Binding constant for LATS1 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
10. | ALA1062843 | Binding | Binding constant for LATS1 kinase domain | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
11. | ALA1049103 | Binding | Inhibition of LATS1 assessed as enzyme activity at 1 uM relative to untreated control | 1 | ALA1155237 | single protein format | Scientific Literature | ||
12. | ALA983611 | Binding | Inhibition of LATS1 at 3 uM | 1 | ALA1142492 | single protein format | Scientific Literature | ||
13. | ALA2210649 | Binding | Inhibition of LATS1 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
14. | ALA2394178 | Binding | Competitive binding affinity to LATS1 (unknown origin) assessed as enzyme remaining bound to anchored active-site ligand at 10 uM relative to control | Homo sapiens | 1 | ALA2390846 | single protein format | Scientific Literature | |
15. | ALA2426975 | Binding | Competitive binding affinity to LATS1 (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 3 | ALA2424622 | single protein format | Scientific Literature | |
16. | ALA3991746 | Binding | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 243 | ALA3991601 | subcellular format | Kuster lab chemical proteomics drug profiling | |
17. | ALA4025204 | Binding | Inhibition of wild-type human partial length LATS1 (Q678 to V1130 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
18. | ALA4034359 | Binding | Inhibition of LATS1 Lysine 1 labelling site (unknown origin) at 10 uM | Homo sapiens | 1 | ALA4033637 | single protein format | Scientific Literature | |
19. | ALA4034360 | Binding | Inhibition of LATS1 Lysine 2 labelling site (unknown origin) at 10 uM | Homo sapiens | 1 | ALA4033637 | single protein format | Scientific Literature | |
20. | ALA4044015 | Binding | Inhibition of wild-type human partial length LATS1 (Q678 to V1130 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | assay format | Scientific Literature |