| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1826200 | B | Activity of LATS1 kinase at 1 uM | 1 | single protein format | Scientific Literature | |||
| 2. | ALA983611 | B | Inhibition of LATS1 at 3 uM | 1 | single protein format | Scientific Literature | |||
| 3. | ALA1062843 | B | Binding constant for LATS1 kinase domain | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 4. | ALA1049103 | B | Inhibition of LATS1 assessed as enzyme activity at 1 uM relative to untreated control | 1 | single protein format | Scientific Literature | |||
| 5. | ALA1166044 | B | Inhibition of LATS1 at 1 uM | 6 | single protein format | Scientific Literature | |||
| 6. | ALA1174813 | B | Inhibition of LATS1 at 10 uM | 2 | single protein format | Scientific Literature | |||
| 7. | ALA1244478 | B | Binding affinity to LATS1 | 7 | single protein format | Scientific Literature | |||
| 8. | ALA1908660 | B | Binding constant for LATS1 kinase domain | 72 | single protein format | Scientific Literature | |||
| 9. | ALA5249655 | B | Inhibition of LATS1 (unknown origin) phosporylation relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA2210649 | B | Inhibition of LATS1 assessed as residual activity at 10 uM relative to control | 1 | single protein format | Scientific Literature | |||
| 11. | ALA2394178 | B | Competitive binding affinity to LATS1 (unknown origin) assessed as enzyme remaining bound to anchored active-site ligand at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA2426975 | B | Competitive binding affinity to LATS1 (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA3631270 | B | Inhibition of LATS (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 14. | ALA3748232 | B | Inhibition of human LATS1 using [KKRNRRLSVA] as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3991746 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 243 | subcellular format | Kuster lab chemical proteomics drug profiling | ||
| 16. | ALA4025204 | B | Inhibition of wild-type human partial length LATS1 (Q678 to V1130 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4034359 | B | Inhibition of LATS1 Lysine 1 labelling site (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4034360 | B | Inhibition of LATS1 Lysine 2 labelling site (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA4044015 | B | Inhibition of wild-type human partial length LATS1 (Q678 to V1130 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4045718 | B | Inhibition of LATS1 conserved Lys1 (ALYATKTLR) in human PBMC at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!