# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA999114 | B | Inhibition of COX1 in microsomes at 100 uM | 2 | ALA1150415 | assay format | Scientific Literature | ||
2. | ALA1775456 | B | Inhibition of COX1 | 2 | ALA1772941 | single protein format | Scientific Literature | ||
3. | ALA2340535 | B | Inhibition of COX-1 (unknown origin)-mediated TMPD oxidation using PGG2 as substrate at 100 uM incubated 15 mins prior to substrate addition measured after 36 secs by spectrophotometric analysis | Homo sapiens | 11 | ALA2331332 | single protein format | Scientific Literature | |
4. | ALA4181303 | A | Inhibition of COX1 in human U937 cells at 10 uM using arachidonic acid as substrate pretreated for 15 mins followed by substrate addition measured after 5 mins relative to control | Homo sapiens | 2 | ALA4177660 | cell-based format | Scientific Literature | |
5. | ALA4187154 | B | Binding affinity to recombinant human COX1 at 10 uM after 3 mins by fluorescence assay relative to control | Homo sapiens | 1 | ALA4184197 | single protein format | Scientific Literature | |
6. | ALA4221874 | A | Inhibition of human U937 cells-derived COX1 assessed as decrease in PGE2 production at 10 uM using arachidonic acid as substrate preincubated for 15 mins prior to substrate addition for 5 mins relative to control | Homo sapiens | 6 | ALA4219124 | assay format | Scientific Literature | |
7. | ALA4363181 | B | Inhibition of COX1 (unknown origin) | Homo sapiens | 1 | ALA4359901 | single protein format | Scientific Literature | |
8. | ALA4739597 | F | Inhibition of mitochondrial COX1 expression in human GFP-labelled MDA-MB-231 cells at 1 uM incubated for 72 hrs under low oxygen condition by Western blot analysis | Homo sapiens | 8 | ALA4732266 | mitochondrion format | Scientific Literature | |
9. | ALA4739598 | F | Inhibition of mitochondrial COX1 expression in human GFP-labelled MDA-MB-231 cells at 30 uM incubated for 72 hrs under low oxygen condition by Western blot analysis | Homo sapiens | 1 | ALA4732266 | mitochondrion format | Scientific Literature | |
10. | ALA4739599 | F | Inhibition of mitochondrial COX1 expression in human GFP-labelled MDA-MB-231 cells at 1 uM incubated for 72 hrs under low oxygen condition by Western blot analysis relative to control | Homo sapiens | 1 | ALA4732266 | mitochondrion format | Scientific Literature | |
11. | ALA4739600 | F | Inhibition of mitochondrial COX1 expression in human GFP-labelled MDA-MB-231 cells at 25 uM incubated for 72 hrs under low oxygen condition by Western blot analysis | Homo sapiens | 1 | ALA4732266 | mitochondrion format | Scientific Literature | |
12. | ALA5104365 | B | Inhibition of COX-1 (unknown origin) | Homo sapiens | 1 | ALA5104091 | single protein format | Scientific Literature | |
13. | ALA5160397 | B | Inhibition of COX1 (unknown origin) at 10 uM | Homo sapiens | 1 | ALA5154772 | single protein format | Scientific Literature | |
14. | ALA5162740 | B | Inhibition of human recombinant COX-1 using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition and measured after 5 mins | Homo sapiens | 1 | ALA5154819 | single protein format | Scientific Literature | |
15. | ALA5162742 | B | Inhibition of COX-1 in human whole blood assessed as reduction in thromboxane B2 production by immunoassay | Homo sapiens | 1 | ALA5154819 | tissue-based format | Scientific Literature | |
16. | ALA5162744 | B | Inhibition of human recombinant COX-1 using [1-14C] arachidonic acid as substrate preincubated for 15 mins followed by substrate addition | Homo sapiens | 1 | ALA5154819 | single protein format | Scientific Literature | |
17. | ALA5164171 | B | Inhibition of human COX1 at 10 uM relative to control | Homo sapiens | 1 | ALA5154849 | single protein format | Scientific Literature |