| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1948744 | B | Binding affinity to LMP7/beta5i in human PC3 cells at 10 to 20 uM after 1.5 hrs by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA981240 | B | Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA | 12 | single protein format | Scientific Literature | |||
| 3. | ALA2184800 | B | Irreversible inhibition of inducible 20S proteasome subunit beta5i chymotrypsin-like activity in human WM cells using suc-LLVY-amc as substrate after 2 hrs by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2343622 | B | Inhibition of chymotrypsin-like activity of human 20S immunoproteasome beta 5 subunit using biotin-(CH2)4-Leu-Leu-Leu-epoxyketone as substrate at 2.5 uM incubated for 5 mins prior to substrate addition measured after 1 hr by ELISA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA2343623 | B | Inhibition of chymotrypsin-like activity of human 20S immunoproteasome beta 5 subunit using biotin-(CH2)4-Leu-Leu-Leu-epoxyketone as substrate at 0.3 uM incubated for 5 mins prior to substrate addition measured after 1 hr by ELISA | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA3240089 | B | Inhibition of beta5i subunit of immunoproteasome (unknown origin) by active-site ELISA | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 7. | ALA3266189 | B | Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate preincubated for 15 mins prior to substrate challenge measured for 120 mins by fluorescence analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3266190 | B | Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate measured for 120 mins by fluorescence analysis | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 9. | ALA3266555 | B | Ratio of Kinact to Ki for immunoproteasome-20S subunit beta5i in human PBMC using suc-LLVY-AMC as substrate measured for 120 mins by fluorescence analysis | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 10. | ALA3266557 | B | Inhibition of immunoproteasome-20S subunit beta5i in human PBMC assessed as substrate hydrolysis using suc-LLVY-AMC as substrate by fluorescence analysis | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 11. | ALA3266559 | B | Inhibition of immunoproteasome 20S subunit beta5i in human Karpas 1106p cell extract at 1 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 12. | ALA3266560 | B | Inhibition of immunoproteasome 20S subunit beta5i in human Karpas 1106p cell extract at 10 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 13. | ALA3266561 | B | Inhibition of immunoproteasome 20S subunit beta5i in human Karpas 1106p cell extract at 100 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 14. | ALA3266562 | B | Inhibition of immunoproteasome 20S subunit beta5i in human Karpas 1106p cell extract at 1 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3266563 | B | Inhibition of immunoproteasome 20S subunit beta5i in human Karpas 1106p cell extract at 10 to 100 nM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3266565 | B | Inhibition of immunoproteasome 20S subunit beta5i in human Karpas 1106p cells assessed as accumulation of polyubiquitinylated proteins at 2.5 to 25 uM after 4 hrs by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA3371271 | B | Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 18. | ALA3371281 | B | Inhibition of proteasome subunit beta-5i in human RPMI8226 cells using BODIPY-NC005 by fluorescent densitometry | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 19. | ALA3997512 | B | Inhibition of LMP7 in human MOLT4 cell lysate after 1 hr by ELISA | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 20. | ALA4123725 | B | Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!