# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2051057 | B | Activity of Mycobacterium tuberculosis CYP125A1 assessed as compound oxidation at 50 uM incubated for 1 hr at 25 degC by GC-MS method | Mycobacterium tuberculosis | 13 | single protein format | Scientific Literature | ||
2. | ALA2051060 | B | Time dependent inhibition of Mycobacterium tuberculosis CYP125A1 at 50 uM incubated up to 3 hrs by HPLC | Mycobacterium tuberculosis | 1 | single protein format | Scientific Literature | ||
3. | ALA2050039 | B | Binding affinity to Mycobacterium tuberculosis CYP125A1 by UV-visible spectrophotometry | Mycobacterium tuberculosis | 2 | single protein format | Scientific Literature | ||
4. | ALA2050042 | B | Binding affinity to Mycobacterium tuberculosis CYP125A1 assessed as type 1 binding mode at 0.05 to 0.2 uM by UV-visible spectrophotometry | Mycobacterium tuberculosis | 11 | single protein format | Scientific Literature | ||
5. | ALA2050045 | B | Binding affinity to Mycobacterium tuberculosis CYP125A1 assessed as type 1a binding mode at > 0.05 to 0.2 uM by UV-visible spectrophotometry | Mycobacterium tuberculosis | 3 | single protein format | Scientific Literature | ||
6. | ALA2050047 | B | Activity of Mycobacterium tuberculosis CYP125A1 assessed as apparent turnover number at 50 uM incubated for 1 hr at 25 degC by GC-MS method | Mycobacterium tuberculosis | 11 | single protein format | Scientific Literature | ||
7. | ALA2050050 | B | Activity of Mycobacterium tuberculosis CYP125A1 assessed as relative apparent turnover number at 50 uM incubated for 1 hr at 25 degC by GC-MS method relative to cholesterol | Mycobacterium tuberculosis | 10 | single protein format | Scientific Literature | ||
8. | ALA979822 | B | Binding affinity to Mycobacterium tuberculosis His4-tagged recombinant CYP125 expressed in Escherichia coli HMS174(DE3) by UV-visible spectral titration method | Mycobacterium tuberculosis | 2 | assay format | Scientific Literature | ||
9. | ALA1647343 | B | Binding affinity to Mycobacterium tuberculosis H37Rv CYP125A1 C429L mutant expressed in Escherichia coli by titration plot analysis | Mycobacterium tuberculosis H37Rv | 1 | assay format | Scientific Literature | ||
10. | ALA1647344 | B | Inhibition of Mycobacterium tuberculosis H37Rv CYP125A1 expressed in Escherichia coli at 200 uM | Mycobacterium tuberculosis H37Rv | 1 | assay format | Scientific Literature | ||
11. | ALA3806587 | B | Binding affinity to Mycobacterium tuberculosis N-terminal His6-tagged CYP125 expressed in Escherichia coli C41 (DE3) cells by UV-visible spectroscopy | Mycobacterium tuberculosis | 1 | cell-based format | Scientific Literature |