| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1803440 | B | Inhibition of Mycobacterium tuberculosis recombinant DXR expressed in Escherichia coli BL21 (DE3) using DXP as substrate and MgCl2 as cofactor preincubated for 10 mins | Mycobacterium tuberculosis | 16 | assay format | Scientific Literature | ||
| 2. | ALA1803584 | B | Inhibition of Mycobacterium tuberculosis recombinant DXR expressed in Escherichia coli BL21 (DE3) using DXP as substrate and Mn2+ as cofactor preincubated for 10 mins | Mycobacterium tuberculosis | 1 | assay format | Scientific Literature | ||
| 3. | ALA1803586 | B | Inhibition of Mycobacterium tuberculosis recombinant DXR expressed in Escherichia coli BL21 (DE3) using DXP as substrate and MgCl2 as cofactor at 100 uM preincubated for 10 mins | Mycobacterium tuberculosis | 32 | assay format | Scientific Literature | ||
| 4. | ALA937902 | B | Inhibition of Mycobacterium tuberculosis DXR assessed as NADPH-dependent conversion of 1-deoxy-D-xylulose 5-phosphate to 2-C-methyl-D-erythritol 4-phosphate by spectrophotometric method | Mycobacterium tuberculosis | 1 | single protein format | Scientific Literature | ||
| 5. | ALA1826115 | B | Inhibition of Mycobacterium tuberculosis DXR assessed as reduction of 1-deoxy-D-xylulose 5-phosphate into 2-C-methyl-D-erythritol-4-phosphate at 100 uM measured for every 5 secs upto 500 secs by spectrophotometry analysis | Mycobacterium tuberculosis | 14 | single protein format | Scientific Literature | ||
| 6. | ALA1826116 | B | Inhibition of Mycobacterium tuberculosis DXR assessed as reduction of 1-deoxy-D-xylulose 5-phosphate into 2-C-methyl-D-erythritol-4-phosphate measured for every 5 secs upto 500 secs by spectrophotometry analysis | Mycobacterium tuberculosis | 6 | single protein format | Scientific Literature | ||
| 7. | ALA2412043 | B | Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate assessed as formation of MEP measured every 5 secs for 180 secs by spectrophotometric analysis | Mycobacterium tuberculosis | 1 | single protein format | Scientific Literature | ||
| 8. | ALA2412045 | B | Binding affinity to Mycobacterium tuberculosis DXR assessed as dissociation constant by spectrofluorimetric analysis in presence of NADPH and MnCl2 | Mycobacterium tuberculosis | 10 | single protein format | Scientific Literature | ||
| 9. | ALA2412047 | B | Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate at 100 uM measured every 5 secs for 250 secs in presence of NADPH relative to control | Mycobacterium tuberculosis | 11 | single protein format | Scientific Literature | ||
| 10. | ALA2412049 | B | Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPH | Mycobacterium tuberculosis | 21 | single protein format | Scientific Literature | ||
| 11. | ALA2434044 | B | Inhibition of Mycobacterium tuberculosis IspC by photometric assay | Mycobacterium tuberculosis | 25 | single protein format | Scientific Literature | ||
| 12. | ALA3106797 | B | Inhibition of Mycobacterium tuberculosis Dxr at 100 uM | Mycobacterium tuberculosis | 3 | single protein format | Scientific Literature | ||
| 13. | ALA3106798 | B | Inhibition of Mycobacterium tuberculosis Dxr | Mycobacterium tuberculosis | 5 | single protein format | Scientific Literature | ||
| 14. | ALA3386562 | B | Inhibition of Mycobacterium tuberculosis IspC using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric analysis | Mycobacterium tuberculosis | 13 | single protein format | Scientific Literature | ||
| 15. | ALA3380669 | B | Inhibition of Mycobacterium tuberculosis Dxr | Mycobacterium tuberculosis | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3423796 | B | Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH oxidation at 100 uM by spectrophotometric analysis | Mycobacterium tuberculosis | 5 | cell-based format | Scientific Literature | ||
| 17. | ALA3423799 | B | Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assessed as NADPH oxidation by spectrophotometric analysis | Mycobacterium tuberculosis | 9 | cell-based format | Scientific Literature | ||
| 18. | ALA4407818 | B | Inhibition of recombinant Mycobacterium tuberculosis IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric assay | Mycobacterium tuberculosis | 15 | assay format | Scientific Literature | ||
| 19. | ALA5226482 | B | Inhibition of Mycobacterium tuberculosis DXR in presence of NADPH by spectrophotometric assay | Mycobacterium tuberculosis | 2 | single protein format | Scientific Literature |
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