# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1002985 | B | Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase 1 encoded by Rv1284 by stopped flow CO2 hydration assay | Mycobacterium tuberculosis | 37 | ALA1138443 | single protein format | Scientific Literature | |
2. | ALA938996 | B | Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 by by stopped flow CO2 hydration assay | Mycobacterium tuberculosis | 20 | ALA1136931 | single protein format | Scientific Literature | |
3. | ALA1048175 | B | Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 by stopped flow CO2 hydration assay | Mycobacterium tuberculosis | 22 | ALA1155354 | single protein format | Scientific Literature | |
4. | ALA1646989 | B | Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv1284 preincubated for 15 mins by stopped-flow CO2 hydrase assay | Mycobacterium tuberculosis | 29 | ALA1641603 | single protein format | Scientific Literature | |
5. | ALA1695104 | B | Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay | Mycobacterium tuberculosis | 27 | ALA1687921 | single protein format | Scientific Literature | |
6. | ALA1695109 | B | Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay relative to phenol | Mycobacterium tuberculosis | 2 | ALA1687921 | single protein format | Scientific Literature | |
7. | ALA1781040 | B | Inhibition of recombinant Mycobacterium tuberculosis Rv1284 carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay at pH 7.5 | Mycobacterium tuberculosis | 1 | ALA1777760 | single protein format | Scientific Literature | |
8. | ALA1815989 | B | Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 at pH 8.3 by stopped flow CO2 hydration assay | Mycobacterium tuberculosis | 1 | ALA1811794 | single protein format | Scientific Literature | |
9. | ALA2183717 | B | Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 pre-incubated for 15 mins by stopped-flow CO2 hydration method | Mycobacterium tuberculosis | 7 | ALA2177016 | single protein format | Scientific Literature | |
10. | ALA3598828 | B | Binding affinity to His6-tagged Mycobacterium tuberculosis Rv1284 expressed in Escherichia coli BL21-AI cells assessed as reduction in melting temperature at 250 uM by SYPRO orange dye based differential scanning fluorimetry | Mycobacterium tuberculosis | 3 | ALA3596190 | cell-based format | Scientific Literature | |
11. | ALA3829730 | B | Inhibition of Mycobacterium tuberculosis beta-carbonic anhydrase Rv1284 preincubated for 15 mins by stopped-flow CO2 hydration assay | Mycobacterium tuberculosis | 3 | ALA3826908 | assay format | Scientific Literature | |
12. | ALA4262458 | B | Binding affinity to recombinant Mycobacterium tuberculosis Rv1284 expressed in Escherichia coli BL21-Al cells assessed as change in melting temperature by SYPRO Orange dye based differential scanning fluorimetric method | Mycobacterium tuberculosis | 15 | ALA4261513 | cell-based format | Scientific Literature | |
13. | ALA4262459 | B | Inhibition of recombinant Mycobacterium tuberculosis Rv1284 expressed in Escherichia coli BL21-Al cells assessed as enzyme residual activity at 25 uM measured for 10 secs by m-cresol purple staining based stopped-flow CO2 hydration assay relative to control | Mycobacterium tuberculosis | 15 | ALA4261513 | cell-based format | Scientific Literature |