# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA953089 | B | Inhibition of ADAM8 | 1 | ALA1141723 | single protein format | Scientific Literature | ||
2. | ALA940654 | B | Inhibition of human recombinant ADAM8 at 200 uM by HxBPyne probe-based competitive activity based protein profiling assay in presence of 5 uM HxBpane competitor | Homo sapiens | 3 | ALA1140994 | single protein format | Scientific Literature | |
3. | ALA3829986 | B | Inhibition of recombinant ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 24 hrs by ELISA | Homo sapiens | 1 | ALA3826879 | cell-based format | Scientific Literature | |
4. | ALA3829987 | B | Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 hrs by ELISA | Homo sapiens | 18 | ALA3826879 | cell-based format | Scientific Literature | |
5. | ALA5229257 | B | Inhibition of human recombinant ADAM8 using PepDAB13 as substrate preincubated with enzyme for 45 mins followed by substrate addition and measured for 6 hrs by fluorometric assay | Homo sapiens | 4 | ALA5226358 | single protein format | Scientific Literature | |
6. | ALA5229266 | B | Inhibition of ADAM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of CD23 shedding by measuring reduction of soluble CD23 release in cell supernatants incubated for 24 hrs by ELISA | Homo sapiens | 4 | ALA5226358 | cell-based format | Scientific Literature | |
7. | ALA5229268 | B | Inhibition of ADAM8 in human MDA-MB-231 cells assessed as inhibition of ERK1/2 phosphorylation at Thr202/Tyr204 residues at 10 uM incubated for 48 hrs by western blot analysis | Homo sapiens | 3 | ALA5226358 | cell-based format | Scientific Literature | |
8. | ALA5229269 | B | Inhibition of ADAM8 in human MDA-MB-231 cells assessed as inhibition of Akt phosphorylation at Ser473 residue at 10 uM incubated for 48 hrs by western blot analysis | Homo sapiens | 3 | ALA5226358 | cell-based format | Scientific Literature |