| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1826085 | B | Activity of PIP5K2B kinase at 1 uM | 1 | single protein format | Scientific Literature | |||
| 2. | ALA981743 | B | Inhibition of PIP5K2B at 3 uM | 1 | single protein format | Scientific Literature | |||
| 3. | ALA1017905 | B | Inhibition of PIP5K2B assessed as enzyme activity relative to control | 2 | single protein format | Scientific Literature | |||
| 4. | ALA1062784 | B | Binding constant for full-length PIP5K2B | Homo sapiens | 38 | single protein format | Scientific Literature | ||
| 5. | ALA1057595 | B | Inhibition of PIP5K2B assessed as enzyme activity at 1 uM relative to untreated control | 1 | single protein format | Scientific Literature | |||
| 6. | ALA1166811 | B | Inhibition of PIP5K2B at 1 uM | 10 | single protein format | Scientific Literature | |||
| 7. | ALA1175218 | B | Inhibition of PIP5K2B at 10 uM | 2 | single protein format | Scientific Literature | |||
| 8. | ALA1244926 | B | Binding affinity to PIP5K2B | 7 | single protein format | Scientific Literature | |||
| 9. | ALA1908612 | B | Binding constant for PIP5K2B kinase domain | 72 | single protein format | Scientific Literature | |||
| 10. | ALA1942473 | B | Inhibition of human PIP4K2B in HL-60 cells lysate assessed as reduction of labeling of acyl-phosphate ATP probe at 100 nM | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA2212495 | B | Inhibition of PIP5K2B assessed as residual activity at 10 uM relative to control | 1 | single protein format | Scientific Literature | |||
| 12. | ALA2394173 | B | Competitive binding affinity to PIP5K2B (unknown origin) assessed as enzyme remaining bound to anchored active-site ligand at 10 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 13. | ALA2429021 | B | Competitive binding affinity to PIP5K2B (unknown origin) at 10 uM in presence of ATP relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 14. | ALA3111943 | B | Inhibition of PIP5K2B (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4025326 | B | Inhibition of wild-type human full length PIP5K2B (M1 to T416 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA4044137 | B | Inhibition of wild-type human full length PIP5K2B (M1 to T416 residues) expressed in Escherichia coli BL21 assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4054930 | B | Inhibition of wild-type human full length PIP5K2B (M1 to T416 residues) expressed in bacterial expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 18. | ALA4157216 | B | Binding affinity to wild-type human full length PIP5K2B (M1 to T416 residues) expressed in bacterial expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4185995 | B | Binding affinity to wild-type human full length PIP5K2B (M1 to T416 residues) expressed in Escherichia coli BL21 at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 20. | ALA4230895 | B | Binding affinity to wild-type human full length PIP5K2B (M1 to T416 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature |
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