# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA855663 | B | Inhibition of human EGLN1 | Homo sapiens | 14 | single protein format | Scientific Literature | ||
2. | ALA855665 | B | Inhibition of EGLN1 | Homo sapiens | 16 | single protein format | Scientific Literature | ||
3. | ALA907266 | B | Inhibition of human EGLN1 | Homo sapiens | 20 | single protein format | Scientific Literature | ||
4. | ALA911914 | B | Inhibition of human EGLN1 | Homo sapiens | 13 | single protein format | Scientific Literature | ||
5. | ALA1804278 | B | Inhibition of GST-tagged PHD2 assessed as inhibition of hydroxylation of biotinylated HIF1alpha CODD peptide at 100 uM after 20 mins by MALDI-TOF technique in presence of 2-oxoglutarate | 4 | single protein format | Scientific Literature | |||
6. | ALA1804279 | B | Inhibition of GST-tagged PHD2 assessed as inhibition of hydroxylation of fluorescein-labeled HIF1alpha CODD peptide after 1 hr by fluorescent polarization assay in presence of 2-oxoglutarate | 2 | single protein format | Scientific Literature | |||
7. | ALA1804281 | B | Inhibition of GST-tagged PHD2 assessed as inhibition of hydroxylation of fluorescein-labeled HIF1alpha CODD peptide at 100 uM after 2 hrs by fluorescent polarization assay in presence of 2-oxoglutarate | 2 | single protein format | Scientific Literature | |||
8. | ALA1804282 | B | Competitive inhibition of GST-tagged PHD2 active site assessed as inhibition of hydroxylation of fluorescein-labeled HIF1alpha CODD peptide at 200 uM after 2 hrs by fluorescent polarization assay in presence of 2-oxoglutarate | 1 | single protein format | Scientific Literature | |||
9. | ALA1804283 | B | Competitive inhibition of GST-tagged PHD2 active site assessed as inhibition of hydroxylation of fluorescein-labeled HIF1alpha CODD peptide at 100 uM after 2 hrs by fluorescent polarization assay in presence of 2-oxoglutarate | 2 | single protein format | Scientific Literature | |||
10. | ALA1804284 | B | Inhibition of PHD2 in human HeLa cells assessed as stabilization of HIF1alpha at 1 mM incubated for 6 hrs under normoxic conditions by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA1804285 | B | Inhibition of PHD2 in human HeLa cells assessed as stabilization of HIF1alpha at 100 uM incubated for 6 hrs under normoxic conditions by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA1798572 | B | Inhibition of human PHD2 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
13. | ALA2034759 | B | Inhibition of human PHD2 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
14. | ALA2045986 | B | Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with compound for 30 mins measured after 2 hrs by time resolved fluorescence analysis | 100 | cell-based format | Scientific Literature | |||
15. | ALA983035 | B | Inhibition of human PHD2 assessed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assay | Homo sapiens | 22 | single protein format | Scientific Literature | ||
16. | ALA946269 | B | Inhibition of human recombinant PHD2 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
17. | ALA946281 | B | Inhibition of 2-oxoglutarate-dependent human recombinant HIF PHD2 preincubated for 1 hr | Homo sapiens | 2 | single protein format | Scientific Literature | ||
18. | ALA983464 | B | Inhibition of PHD2 by fluorescence energy transfer analysis | 13 | single protein format | Scientific Literature | |||
19. | ALA1045056 | B | Inhibition of human PHD2 catalytic domain (181-426) by FRET assay | Homo sapiens | 16 | single protein format | Scientific Literature | ||
20. | ALA1047005 | B | Binding affinity to human PHD2 by nondenaturing ESI-MS | Homo sapiens | 9 | single protein format | Scientific Literature |